Phillygenin

Modify Date: 2025-08-26 18:11:23

Phillygenin Structure
Phillygenin structure
 Common Name Phillygenin
CAS Number 487-39-8 Molecular Weight 372.412
Density 1.2±0.1 g/cm3 Boiling Point 534.9±50.0 °C at 760 mmHg
Molecular Formula C21H24O6 Melting Point 133ºC
MSDS N/A Flash Point 277.3±30.1 °C

 Use of Phillygenin


Phillygenin is an active ingredient from Forsythia with many medicinal properties, such as antioxidant, reducing blood lipid, inhibition of low density lipoprotein oxidation.In vitro : 1) Phillygenin shows a greater inhibition on mouse B16 melanoma cells potential than vincristine.2) phillygenin had notable scavenging activity against DPPH, ABTS radicals, as well as potent reducing power in FRAP assay.In vivo: The reference for rat is 5.6 mg/m l ( i.v).

 Names

Name 4-[(3S,3aR,6R,6aR)-6-(3,4-dimethoxyphenyl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan-3-yl]-2-methoxyphenol
Synonym More Synonyms

 Phillygenin Biological Activity

Description Phillygenin is an active ingredient from Forsythia with many medicinal properties, such as antioxidant, reducing blood lipid, inhibition of low density lipoprotein oxidation.In vitro : 1) Phillygenin shows a greater inhibition on mouse B16 melanoma cells potential than vincristine.2) phillygenin had notable scavenging activity against DPPH, ABTS radicals, as well as potent reducing power in FRAP assay.In vivo: The reference for rat is 5.6 mg/m l ( i.v).
Related Catalog
References

[1]. Ye LH et al. Determination of phillygenin in rat plasma by high-performance liquid chromatography and its application to pharmacokinetic studies. Eur J Drug Metab Pharmacokinet, 2013 Sep, 38(3):201-7.

[2]. Song W et al. Interaction between phillygenin and human serum albumin based on spectroscopic and molecular docking. Spectrochim Acta A Mol Biomol Spectrosc, 2012 Jan, 85(1):120-6.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 534.9±50.0 °C at 760 mmHg
Melting Point 133ºC
Molecular Formula C21H24O6
Molecular Weight 372.412
Flash Point 277.3±30.1 °C
Exact Mass 372.157288
PSA 66.38000
LogP 2.31
Vapour Pressure 0.0±1.5 mmHg at 25°C
Index of Refraction 1.570

 Synonyms

philligenin
sylvatesmin
Phillygenol
4-[(1S,3aR,4R,6aR)-4-(3,4-Dimethoxyphenyl)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]-2-methoxyphenol
(+)-Phillygenin
Epipinoresinol methyl ether
Phenol, 4-[(1S,3aR,4R,6aR)-4-(3,4-dimethoxyphenyl)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]-2-methoxy-
phylligenin
Phillygenin
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Chemsrc provides Phillygenin(CAS#:487-39-8) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of Phillygenin are included as well.>> amp version: Phillygenin

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