Hydroxymetronidazole

Modify Date: 2024-01-02 23:27:24

Hydroxymetronidazole structure	Common Name	Hydroxymetronidazole
	CAS Number	4812-40-2	Molecular Weight	187.15300
	Density	1.61g/cm3	Boiling Point	475.2ºC at 760mmHg
	Molecular Formula	C₆H₉N₃O₄	Melting Point	118-121ºC
	MSDS	Chinese USA	Flash Point	241.2ºC

Use of Hydroxymetronidazole

Hydroxymetronidazole (Metronidazole-OH) is a metabolite of Metronidazole belonging to the class of nitroimidazoles. Hydroxymetronidazole can be used for the research of certain bacterial and protozoal diseases in poultry, swine dysentery and genital trichomoniasis in cattle[1].

Name	Hydroxy Metronidazole
Synonym	More Synonyms

Description	Hydroxymetronidazole (Metronidazole-OH) is a metabolite of Metronidazole belonging to the class of nitroimidazoles. Hydroxymetronidazole can be used for the research of certain bacterial and protozoal diseases in poultry, swine dysentery and genital trichomoniasis in cattle[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
References	[1]. Rodrigo H M M Granja, et al. Determination and confirmation of metronidazole, dimetridazole, ronidazole and their metabolites in bovine muscle by LC-MS/MS. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2013;30(6):970-6.

Density	1.61g/cm3
Boiling Point	475.2ºC at 760mmHg
Melting Point	118-121ºC
Molecular Formula	C₆H₉N₃O₄
Molecular Weight	187.15300
Flash Point	241.2ºC
Exact Mass	187.05900
PSA	104.10000
Index of Refraction	1.643
Storage condition	-20?C Freezer

CHEMICAL IDENTIFICATION

RTECS NUMBER :: NI5568000

CHEMICAL NAME :: Imidazole-1-ethanol, 2-hydroxymethyl-5-nitro-

CAS REGISTRY NUMBER :: 4812-40-2

BEILSTEIN REFERENCE NO. :: 0883934

LAST UPDATED :: 199612

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C6-H9-N3-O4

MOLECULAR WEIGHT :: 187.18

WISWESSER LINE NOTATION :: T5N CNJ A2Q B1Q ENW

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Bacteria - Klebsiella pneumoniae

DOSE/DURATION :: 10 umol/L/20H

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 66,207,1979

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Safety Phrases	24/25
RIDADR	NONH for all modes of transport
RTECS	NI5568000

methyl-(2-hydro...

CAS#:147124-51-4

~77%

Hydroxymetronidazole

CAS#:4812-40-2

Literature: Hambalek; Just Synthetic Communications, 1993 , vol. 23, # 2 p. 209 - 215

2-(2-(hydroxyme...

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Hydroxymetronidazole

CAS#:4812-40-2

Literature: Hambalek; Just Synthetic Communications, 1993 , vol. 23, # 2 p. 209 - 215

ethyl-(2-bromom...

CAS#:147124-49-0

Hydroxymetronidazole

CAS#:4812-40-2

Literature: Hambalek; Just Synthetic Communications, 1993 , vol. 23, # 2 p. 209 - 215

ethyl 2-(2-meth...

CAS#:1016-40-6

Hydroxymetronidazole

CAS#:4812-40-2

Literature: Hambalek; Just Synthetic Communications, 1993 , vol. 23, # 2 p. 209 - 215

Precursor 3
CAS#:147124-51-4 methyl-(2-hydro... CAS#:147124-50-3 2-(2-(hydroxyme... CAS#:1016-40-6 ethyl 2-(2-meth...
DownStream 0

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2-[2-(hydroxymethyl)-5-nitroimidazol-1-yl]ethanol