Hexane-1,6-diyldiphosphonic acid
Modify Date: 2025-08-25 08:05:25
Hexane-1,6-diyldiphosphonic acid structure
|
Common Name | Hexane-1,6-diyldiphosphonic acid | ||
|---|---|---|---|---|
| CAS Number | 4721-22-6 | Molecular Weight | 246.13500 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C6H16O6P2 | Melting Point | 206 °C | |
| MSDS | N/A | Flash Point | N/A | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Use of Hexane-1,6-diyldiphosphonic acidHexane-1,6-diyldiphosphonic acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
| Name | 6-phosphonohexylphosphonic acid |
|---|---|
| Synonym | More Synonyms |
| Description | Hexane-1,6-diyldiphosphonic acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
Alkyl-Chain |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Melting Point | 206 °C |
|---|---|
| Molecular Formula | C6H16O6P2 |
| Molecular Weight | 246.13500 |
| Exact Mass | 246.04200 |
| PSA | 134.68000 |
| LogP | 0.90220 |
| InChIKey | WDYVUKGVKRZQNM-UHFFFAOYSA-N |
| SMILES | O=P(O)(O)CCCCCCP(=O)(O)O |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P280-P305 + P351 + P338-P337 + P313 |
| Hazard Codes | C |
| RIDADR | NONH for all modes of transport |
|
~%
Hexane-1,6-diyl... CAS#:4721-22-6 |
| Literature: Kosolapoff,G.M.; Brown,A.D. Journal of the Chemical Society [Section] C: Organic, 1966 , p. 757 - 759 |
|
~89%
Hexane-1,6-diyl... CAS#:4721-22-6 |
| Literature: Villemin, Didier; Moreau, Bernard; Kaid, M'Hamed; Didi, Mohamed Amine Phosphorus, Sulfur and Silicon and the Related Elements, 2010 , vol. 185, # 8 p. 1583 - 1586 |
|
~%
Hexane-1,6-diyl... CAS#:4721-22-6 |
| Literature: Horne; Blanchard Journal of the American Chemical Society, 1996 , vol. 118, # 50 p. 12788 - 12795 |
| Precursor 3 | |
|---|---|
| DownStream 0 | |
| 1,6-hexylenediphosphonic acid |
| 1,6-HEXYLENEBISPHOSPHONIC ACID |
| hexane-1,6-diylbisphosphonic acid |
| hexane-1,6-diyldiphosphonic acid |
| 1,6-Hexanebisphosphonic acid |
| 1,6-Diphosphono-hexan |
| 1,6-hexanediphosphonic acid |
| hexane-1,6-bisphosphonic acid |