4721-22-6
4721-22-6 structure
- Name: Hexane-1,6-diyldiphosphonic acid
- Chemical Name: 6-phosphonohexylphosphonic acid
- CAS Number: 4721-22-6
- Molecular Formula: C6H16O6P2
- Molecular Weight: 246.13500
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2016-01-03 04:32:21
- Modify Date: 2025-08-25 08:05:25
-
Hexane-1,6-diyldiphosphonic acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | 6-phosphonohexylphosphonic acid |
|---|---|
| Synonyms |
1,6-hexylenediphosphonic acid
1,6-HEXYLENEBISPHOSPHONIC ACID hexane-1,6-diylbisphosphonic acid hexane-1,6-diyldiphosphonic acid 1,6-Hexanebisphosphonic acid 1,6-Diphosphono-hexan 1,6-hexanediphosphonic acid hexane-1,6-bisphosphonic acid |
| Description | Hexane-1,6-diyldiphosphonic acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
Alkyl-Chain |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Melting Point | 206 °C |
|---|---|
| Molecular Formula | C6H16O6P2 |
| Molecular Weight | 246.13500 |
| Exact Mass | 246.04200 |
| PSA | 134.68000 |
| LogP | 0.90220 |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P280-P305 + P351 + P338-P337 + P313 |
| Hazard Codes | C |
| RIDADR | NONH for all modes of transport |
