5MPN
Modify Date: 2025-08-25 18:41:24
5MPN structure
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Common Name | 5MPN | ||
|---|---|---|---|---|
| CAS Number | 47208-82-2 | Molecular Weight | 305.329 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 493.8±40.0 °C at 760 mmHg | |
| Molecular Formula | C15H19N3O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 252.4±27.3 °C | |
Use of 5MPN5MPN is a first-in-class, selective, competitive, orally available inhibitor of PFKFB4 with Ki of 8.6 uM, does not inhibit PFK-1 or PFKFB3; suppresses the glycolysis and proliferation of multiple human cancer cell lines but not non-transformed epithelial cells in vitro, suppresses the glucose metabolism and growth of tumors in mice. |
| Name | MFCD00089445 |
|---|---|
| Synonym | More Synonyms |
| Description | 5MPN is a first-in-class, selective, competitive, orally available inhibitor of PFKFB4 with Ki of 8.6 uM, does not inhibit PFK-1 or PFKFB3; suppresses the glycolysis and proliferation of multiple human cancer cell lines but not non-transformed epithelial cells in vitro, suppresses the glucose metabolism and growth of tumors in mice. |
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| References | References 1. Chesney J, et al. Oncotarget. 2015 Jul 20;6(20):18001-11. View Related Products by Target Other Targets |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 493.8±40.0 °C at 760 mmHg |
| Molecular Formula | C15H19N3O4 |
| Molecular Weight | 305.329 |
| Flash Point | 252.4±27.3 °C |
| Exact Mass | 305.137543 |
| LogP | 3.59 |
| Vapour Pressure | 0.0±1.3 mmHg at 25°C |
| Index of Refraction | 1.607 |
| Hazard Codes | Xi |
|---|
| 5-[(8-Methoxy-4-quinolinyl)amino]pentyl nitrate |
| MFCD00089445 |
| 5-(N-(8-METHOXY-4-QUINOLYL)AMINO)PENTYL NITRATE |
| 1-Pentanol, 5-[(8-methoxy-4-quinolinyl)amino]-, nitrate (ester) |