Simvastatin Acyl-β-D-glucuronide

Modify Date: 2024-02-08 20:33:40

Simvastatin Acyl-β-D-glucuronide Structure
Simvastatin Acyl-β-D-glucuronide structure
Common Name Simvastatin Acyl-β-D-glucuronide
CAS Number 463962-56-3 Molecular Weight 612.71
Density N/A Boiling Point N/A
Molecular Formula C31H48O12 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Simvastatin Acyl-β-D-glucuronide


Simvastatin Acyl-β-D-glucuronide is a metabolite of Simvastatin. Simvastatin is a competitive inhibitor of HMG-CoA reductase with a Ki of 0.2 nM[1][2].

 Names

Name Simvastatin Acyl-β-D-glucuronide

 Simvastatin Acyl-β-D-glucuronide Biological Activity

Description Simvastatin Acyl-β-D-glucuronide is a metabolite of Simvastatin. Simvastatin is a competitive inhibitor of HMG-CoA reductase with a Ki of 0.2 nM[1][2].
Related Catalog
References

[1]. Prueksaritanont T, Subramanian R, Fang X, et al. Glucuronidation of statins in animals and humans: a novel mechanism of statin lactonization. Drug Metab Dispos. 2002;30(5):505‐512.

 Chemical & Physical Properties

Molecular Formula C31H48O12
Molecular Weight 612.71