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463962-56-3

463962-56-3 structure
463962-56-3 structure
  • Name: Simvastatin Acyl-β-D-glucuronide
  • Chemical Name: Simvastatin Acyl-β-D-glucuronide
  • CAS Number: 463962-56-3
  • Molecular Formula: C31H48O12
  • Molecular Weight: 612.71
  • Catalog: Research Areas Others
  • Create Date: 2020-06-01 15:04:45
  • Modify Date: 2024-02-08 20:33:40
  • Simvastatin Acyl-β-D-glucuronide is a metabolite of Simvastatin. Simvastatin is a competitive inhibitor of HMG-CoA reductase with a Ki of 0.2 nM[1][2].

Name Simvastatin Acyl-β-D-glucuronide
Description Simvastatin Acyl-β-D-glucuronide is a metabolite of Simvastatin. Simvastatin is a competitive inhibitor of HMG-CoA reductase with a Ki of 0.2 nM[1][2].
Related Catalog
References

[1]. Prueksaritanont T, Subramanian R, Fang X, et al. Glucuronidation of statins in animals and humans: a novel mechanism of statin lactonization. Drug Metab Dispos. 2002;30(5):505‐512.

Molecular Formula C31H48O12
Molecular Weight 612.71