Simvastatin Acyl-β-D-glucuronide

Names

[ Name ]:
Simvastatin Acyl-β-D-glucuronide

Biological Activity

[Description]:

Simvastatin Acyl-β-D-glucuronide is a metabolite of Simvastatin. Simvastatin is a competitive inhibitor of HMG-CoA reductase with a Ki of 0.2 nM[1][2].

[Related Catalog]:

Research Areas >> Others

[References]

[1]. Prueksaritanont T, Subramanian R, Fang X, et al. Glucuronidation of statins in animals and humans: a novel mechanism of statin lactonization. Drug Metab Dispos. 2002;30(5):505‐512.

Chemical & Physical Properties

[ Molecular Formula ]:
C₃₁H₄₈O₁₂

[ Molecular Weight ]:
612.71

Simvastatin Acyl-β-D-glucuronide

Names

Biological Activity

Chemical & Physical Properties

Related Compounds