NSC 15364

Modify Date: 2025-09-12 19:11:11

NSC 15364 Structure
NSC 15364 structure
Common Name NSC 15364
CAS Number 4550-72-5 Molecular Weight 242.277
Density 1.4±0.1 g/cm3 Boiling Point 381.4±27.0 °C at 760 mmHg
Molecular Formula C13H14N4O Melting Point N/A
MSDS N/A Flash Point 184.5±23.7 °C

 Use of NSC 15364


NSC 15364 is an inhibitor of VDAC1 oligomerization and apoptosis[1].

 Names

Name 1,3-bis(4-aminophenyl)urea
Synonym More Synonyms

 NSC 15364 Biological Activity

Description NSC 15364 is an inhibitor of VDAC1 oligomerization and apoptosis[1].
Related Catalog
In Vitro Mitochondrial membrane protein voltage-dependent anion channel 1 (VDAC1) oligomerization represents a prime target for agents designed to modulate apoptosis[1].
References

[1]. Ben-Hail D, et al. Novel Compounds Targeting the Mitochondrial Protein VDAC1 Inhibit Apoptosis and Protect against Mitochondrial Dysfunction. J Biol Chem. 2016 Nov 25;291(48):24986-25003.

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 381.4±27.0 °C at 760 mmHg
Molecular Formula C13H14N4O
Molecular Weight 242.277
Flash Point 184.5±23.7 °C
Exact Mass 242.116760
PSA 93.17000
LogP -0.50
Vapour Pressure 0.0±0.9 mmHg at 25°C
Index of Refraction 1.785
Storage condition -20℃

 Safety Information

HS Code 2924299090

 Synthetic Route

~96%

NSC 15364 Structure

NSC 15364

CAS#:4550-72-5

Literature: Rodriguez, Fernando; Rozas, Isabel; Kaiser, Marcel; Brun, Reto; Nguyen, Binh; Wilson, W. David; Garcia, Rory Nelson; Dardonville, Christophe Journal of Medicinal Chemistry, 2008 , vol. 51, # 4 p. 909 - 923

~73%

NSC 15364 Structure

NSC 15364

CAS#:4550-72-5

Literature: Khan, S. Rehman; Gilani; Inayat, Asma; Waheed, Shaheena Pakistan Journal of Scientific and Industrial Research, 2006 , vol. 49, # 5 p. 319 - 323

~%

NSC 15364 Structure

NSC 15364

CAS#:4550-72-5

Literature: Turner, William R.; Werbel, Leslie M. Journal of Medicinal Chemistry, 1985 , vol. 28, # 11 p. 1728 - 1740

~%

NSC 15364 Structure

NSC 15364

CAS#:4550-72-5

Literature: Uno, Masaharu; Koma, Yosuke; Ban, Hyun Seung; Nakamura, Hiroyuki Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 16 p. 5169 - 5173

~%

NSC 15364 Structure

NSC 15364

CAS#:4550-72-5

Literature: Schiff,H.; Ostrogovich Justus Liebigs Annalen der Chemie, 1896 , vol. 293, p. 374 Chemische Berichte, 1894 , vol. 27, p. 398

~%

NSC 15364 Structure

NSC 15364

CAS#:4550-72-5

Literature: Soloduschenkow et al. Zhurnal Prikladnoi Khimii (Sankt-Peterburg, Russian Federation), 1957 , vol. 30, p. 1361,1365; engl.Ausg.S.1430,1432

~%

NSC 15364 Structure

NSC 15364

CAS#:4550-72-5

Literature: Schiff,H.; Ostrogovich Justus Liebigs Annalen der Chemie, 1896 , vol. 293, p. 374 Chemische Berichte, 1894 , vol. 27, p. 398

~%

NSC 15364 Structure

NSC 15364

CAS#:4550-72-5

Literature: Schiff,H.; Ostrogovich Justus Liebigs Annalen der Chemie, 1896 , vol. 293, p. 374 Chemische Berichte, 1894 , vol. 27, p. 398

 Customs

HS Code 2924299090
Summary 2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Synonyms

1,3-Bis(p-aminophenyl)urea
N,N'-Bis(4-aminophenyl)urea
1,3-bis-(4-aminophenyl)urea
1,3-Bis(4-aminophenyl)urea
Urea, N,N'-bis(4-aminophenyl)-
4,4'-diaminodiphenylurea
Carbanilide,4'-diamino
NSC 15364
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