4550-72-5
4550-72-5 structure
- Name: NSC 15364
- Chemical Name: 1,3-bis(4-aminophenyl)urea
- CAS Number: 4550-72-5
- Molecular Formula: C13H14N4O
- Molecular Weight: 242.277
- Catalog: Signaling Pathways Apoptosis Apoptosis
- Create Date: 2016-10-30 17:18:07
- Modify Date: 2025-09-12 19:11:11
-
NSC 15364 is an inhibitor of VDAC1 oligomerization and apoptosis[1].
| Name | 1,3-bis(4-aminophenyl)urea |
|---|---|
| Synonyms |
1,3-Bis(p-aminophenyl)urea
N,N'-Bis(4-aminophenyl)urea 1,3-bis-(4-aminophenyl)urea 1,3-Bis(4-aminophenyl)urea Urea, N,N'-bis(4-aminophenyl)- 4,4'-diaminodiphenylurea Carbanilide,4'-diamino NSC 15364 |
| Description | NSC 15364 is an inhibitor of VDAC1 oligomerization and apoptosis[1]. |
|---|---|
| Related Catalog | |
| In Vitro | Mitochondrial membrane protein voltage-dependent anion channel 1 (VDAC1) oligomerization represents a prime target for agents designed to modulate apoptosis[1]. |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 381.4±27.0 °C at 760 mmHg |
| Molecular Formula | C13H14N4O |
| Molecular Weight | 242.277 |
| Flash Point | 184.5±23.7 °C |
| Exact Mass | 242.116760 |
| PSA | 93.17000 |
| LogP | -0.50 |
| Vapour Pressure | 0.0±0.9 mmHg at 25°C |
| Index of Refraction | 1.785 |
| Storage condition | -20℃ |
| HS Code | 2924299090 |
|---|
|
~96%
4550-72-5 |
| Literature: Rodriguez, Fernando; Rozas, Isabel; Kaiser, Marcel; Brun, Reto; Nguyen, Binh; Wilson, W. David; Garcia, Rory Nelson; Dardonville, Christophe Journal of Medicinal Chemistry, 2008 , vol. 51, # 4 p. 909 - 923 |
|
~73%
4550-72-5 |
| Literature: Khan, S. Rehman; Gilani; Inayat, Asma; Waheed, Shaheena Pakistan Journal of Scientific and Industrial Research, 2006 , vol. 49, # 5 p. 319 - 323 |
|
~%
4550-72-5 |
| Literature: Turner, William R.; Werbel, Leslie M. Journal of Medicinal Chemistry, 1985 , vol. 28, # 11 p. 1728 - 1740 |
|
~%
4550-72-5 |
| Literature: Uno, Masaharu; Koma, Yosuke; Ban, Hyun Seung; Nakamura, Hiroyuki Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 16 p. 5169 - 5173 |
|
~%
4550-72-5 |
| Literature: Schiff,H.; Ostrogovich Justus Liebigs Annalen der Chemie, 1896 , vol. 293, p. 374 Chemische Berichte, 1894 , vol. 27, p. 398 |
|
~%
4550-72-5 |
| Literature: Soloduschenkow et al. Zhurnal Prikladnoi Khimii (Sankt-Peterburg, Russian Federation), 1957 , vol. 30, p. 1361,1365; engl.Ausg.S.1430,1432 |
|
~%
4550-72-5 |
| Literature: Schiff,H.; Ostrogovich Justus Liebigs Annalen der Chemie, 1896 , vol. 293, p. 374 Chemische Berichte, 1894 , vol. 27, p. 398 |
|
~%
4550-72-5 |
| Literature: Schiff,H.; Ostrogovich Justus Liebigs Annalen der Chemie, 1896 , vol. 293, p. 374 Chemische Berichte, 1894 , vol. 27, p. 398 |
| Precursor 8 | |
|---|---|
| DownStream 1 | |
| HS Code | 2924299090 |
|---|---|
| Summary | 2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |