IR415

Modify Date: 2024-09-16 16:24:24

IR415 Structure
IR415 structure
 Common Name IR415
CAS Number 452967-14-5 Molecular Weight 296.34
Density N/A Boiling Point N/A
Molecular Formula C13H14F2N4S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of IR415


IR415 is a novel small molecule inhibitor of HBV virus replication that blocks hepatitis B virus X protein (HBx, Kd=2 nM) mediated RNAi suppression, reverses the inhibitory effect of HBx protein on activity of the Dicer endoribonuclease; exhibits a marked depletion of HBV core protein synthesis and down-regulation of pre-genomic HBV RNA in HBV-infected HepG2 cells, selectively targets HBx in a concentration-dependent manner.

 Names

Name IR415
Synonym More Synonyms

 IR415 Biological Activity

Description IR415 is a novel small molecule inhibitor of HBV virus replication that blocks hepatitis B virus X protein (HBx, Kd=2 nM) mediated RNAi suppression, reverses the inhibitory effect of HBx protein on activity of the Dicer endoribonuclease; exhibits a marked depletion of HBV core protein synthesis and down-regulation of pre-genomic HBV RNA in HBV-infected HepG2 cells, selectively targets HBx in a concentration-dependent manner.
References References 1. Ghosh S, et al. J Biol Chem. 2017 Jul 28;292(30):12577-12588. View Related Products by Target HBV

 Chemical & Physical Properties

Molecular Formula C13H14F2N4S
Molecular Weight 296.34

 Safety Information

Hazard Codes Xi

 Synonyms

MFCD00238878
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.
Top Suppliers:I want be here

Get all suppliers and price by the below link:

IR415 suppliers

IR415 price

Related Compounds: More...
Ethyl 2-((5-(3-(2-fluorophenyl)-1,2,4-oxadiazol-5-yl)pyrimidin-4-yl)amino)acetate
2034571-69-0
5-[3-(2-fluorophenyl)-1,2,4-oxadiazol-5-yl]-N-[2-(5-methoxy-1H-indol-3-yl)ethyl]pyrimidin-4-amine
2034447-05-5
3-(2-Fluorophenyl)-5-(4-thiomorpholinopyrimidin-5-yl)-1,2,4-oxadiazole
2034511-89-0
5-(3-(2-fluorophenyl)-1,2,4-oxadiazol-5-yl)-N-(2-(thiophen-2-yl)ethyl)pyrimidin-4-amine
2034341-25-6
5-(3-(2-fluorophenyl)-1,2,4-oxadiazol-5-yl)-N-(2-(2-methoxyphenoxy)ethyl)pyrimidin-4-amine
2034511-98-1
N-(2-bromobenzyl)-5-(3-(2-fluorophenyl)-1,2,4-oxadiazol-5-yl)pyrimidin-4-amine
2034341-31-4
N-(2,3-dihydro-1H-inden-1-yl)-5-[3-(2-fluorophenyl)-1,2,4-oxadiazol-5-yl]pyrimidin-4-amine
2034244-55-6
N-(2-(3,5-dimethylisoxazol-4-yl)ethyl)-5-(3-(2-fluorophenyl)-1,2,4-oxadiazol-5-yl)pyrimidin-4-amine
2034244-58-9
5-(3-(2-fluorophenyl)-1,2,4-oxadiazol-5-yl)-N-(1-(thiophen-2-yl)propyl)pyrimidin-4-amine
2034571-82-7
N-(2-(4-(3-(pyridin-3-yl)-1,2,4-oxadiazol-5-yl)-1H-1,2,3-triazol-1-yl)ethyl)furan-2-carboxamide
2034478-62-9
Chemsrc provides IR415(CAS#:452967-14-5) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of IR415 are included as well.>> amp version: IR415

Home | MSDS/SDS Database Search | Journals | Product Classification | Biologically Active Compounds | Selling Leads | About Us | Disclaimer

Copyright © 2024 ChemSrc All Rights Reserved