4-Methyl-6-phenyl-2H-pyranone

Modify Date: 2024-01-09 11:00:55

4-Methyl-6-phenyl-2H-pyranone Structure
4-Methyl-6-phenyl-2H-pyranone structure
Common Name 4-Methyl-6-phenyl-2H-pyranone
CAS Number 4467-30-5 Molecular Weight 186.20700
Density N/A Boiling Point N/A
Molecular Formula C12H10O2 Melting Point 87 °C
MSDS N/A Flash Point N/A

 Use of 4-Methyl-6-phenyl-2H-pyranone


4-Methyl-6-phenyl-2H-pyranone can be used for the synthesis of N-hydroxypyridone derivatives, which can protect astrocytes against hydrogen peroxide-induced toxicity via improved mitochondrial functionality[1].

 Names

Name 4-methyl-6-phenylpyran-2-one
Synonym More Synonyms

 4-Methyl-6-phenyl-2H-pyranone Biological Activity

Description 4-Methyl-6-phenyl-2H-pyranone can be used for the synthesis of N-hydroxypyridone derivatives, which can protect astrocytes against hydrogen peroxide-induced toxicity via improved mitochondrial functionality[1].
Related Catalog
References

[1]. Singh S, et al. Discovery of a novel series of N-hydroxypyridone derivatives protecting astrocytes against hydrogen peroxide-induced toxicity via improved mitochondrial functionality. Bioorg Med Chem. 2017;25(4):1394-1405.

 Chemical & Physical Properties

Melting Point 87 °C
Molecular Formula C12H10O2
Molecular Weight 186.20700
Exact Mass 186.06800
PSA 30.21000
LogP 2.61520

 Safety Information

Hazard Codes Xi

 Synthetic Route

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4-Methyl-6-phenyl-2H-pyranone Structure

4-Methyl-6-phen...

CAS#:4467-30-5

Literature: Zheng, Baisong; Yao, Yuan; Liu, Zhen; Deng, Lisheng; Anglin, Justin L.; Jiang, Hong; Prasad, B.V. Venkataram; Song, Yongcheng ACS Medicinal Chemistry Letters, 2013 , vol. 4, # 6 p. 542 - 546

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4-Methyl-6-phenyl-2H-pyranone Structure

4-Methyl-6-phen...

CAS#:4467-30-5

Literature: Albaugh-Robertson, Pamela; Katzenellenbogen, John A. Tetrahedron Letters, 1982 , vol. 23, # 7 p. 723 - 726

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4-Methyl-6-phenyl-2H-pyranone Structure

4-Methyl-6-phen...

CAS#:4467-30-5

Literature: Zheng, Baisong; Yao, Yuan; Liu, Zhen; Deng, Lisheng; Anglin, Justin L.; Jiang, Hong; Prasad, B.V. Venkataram; Song, Yongcheng ACS Medicinal Chemistry Letters, 2013 , vol. 4, # 6 p. 542 - 546

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4-Methyl-6-phenyl-2H-pyranone Structure

4-Methyl-6-phen...

CAS#:4467-30-5

Literature: Zheng, Baisong; Yao, Yuan; Liu, Zhen; Deng, Lisheng; Anglin, Justin L.; Jiang, Hong; Prasad, B.V. Venkataram; Song, Yongcheng ACS Medicinal Chemistry Letters, 2013 , vol. 4, # 6 p. 542 - 546

 Synonyms

4-methyl-6-phenyl-pyran-2-one
4-methyl-6-phenyl-2H-2-pyranone
4-Methyl-6-phenyl-2-pyron
2H-Pyran-2-one,4-methyl-6-phenyl