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4-Methyl-6-phenyl-2H-pyranone

Names

[ CAS No. ]:
4467-30-5

[ Name ]:
4-Methyl-6-phenyl-2H-pyranone

[Synonym ]:
4-methyl-6-phenyl-pyran-2-one
4-methyl-6-phenyl-2H-2-pyranone
4-Methyl-6-phenyl-2-pyron
2H-Pyran-2-one,4-methyl-6-phenyl

Biological Activity

[Description]:

4-Methyl-6-phenyl-2H-pyranone can be used for the synthesis of N-hydroxypyridone derivatives, which can protect astrocytes against hydrogen peroxide-induced toxicity via improved mitochondrial functionality[1].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[References]

[1]. Singh S, et al. Discovery of a novel series of N-hydroxypyridone derivatives protecting astrocytes against hydrogen peroxide-induced toxicity via improved mitochondrial functionality. Bioorg Med Chem. 2017;25(4):1394-1405.

Chemical & Physical Properties

[ Melting Point ]:
87 °C

[ Molecular Formula ]:
C12H10O2

[ Molecular Weight ]:
186.20700

[ Exact Mass ]:
186.06800

[ PSA ]:
30.21000

[ LogP ]:
2.61520

Safety Information

[ Hazard Codes ]:
Xi

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds

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