MRS-2365
Modify Date: 2024-01-08 11:53:07
MRS-2365 structure
|
Common Name | MRS-2365 | ||
|---|---|---|---|---|
| CAS Number | 436847-09-5 | Molecular Weight | 549.27600 | |
| Density | 2.37±0.1 g/cm3(Predicted) | Boiling Point | 875.5±75.0 °C(Predicted) | |
| Molecular Formula | C13H16N5Na3O9P2S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of MRS-2365MRS2365 is a potent and selective P2Y1 receptor agonist with an EC50 of 0.4 nM. MRS2365 shows little agonist or antagonist activity at the P2Y12 or P2Y13 receptors[1][2]. |
| Name | MRS 2365,[[(1R,2R,3S,4R,5S)-4-[6-Amino-2-(methylthio)-9H-purin-9-yl]-2,3-dihydroxybicyclo[3.1.0]hex-1-yl]methyl]diphosphoricacidmonoestertrisodiumsalt |
|---|---|
| Synonym | More Synonyms |
| Description | MRS2365 is a potent and selective P2Y1 receptor agonist with an EC50 of 0.4 nM. MRS2365 shows little agonist or antagonist activity at the P2Y12 or P2Y13 receptors[1][2]. |
|---|---|
| Related Catalog | |
| In Vitro | Selective activation of the P2Y1 receptor also is suggested from functional studies of human platelets as MRS2365 potently induced shape change without causing the sustained aggregation that is a hallmark of simultaneous activation of the P2Y1 and P2Y12 receptors by ADP or by previously studied ADP analogues[2]. |
| References |
| Density | 2.37±0.1 g/cm3(Predicted) |
|---|---|
| Boiling Point | 875.5±75.0 °C(Predicted) |
| Molecular Formula | C13H16N5Na3O9P2S |
| Molecular Weight | 549.27600 |
| Exact Mass | 548.98400 |
| PSA | 276.78000 |
| LogP | 1.53530 |
| Storage condition | 2-8°C |
| MRS-2365 |