6-Hydroxykaempferol

Modify Date: 2024-01-09 11:56:14

6-Hydroxykaempferol Structure
6-Hydroxykaempferol structure
Common Name 6-Hydroxykaempferol
CAS Number 4324-55-4 Molecular Weight 302.23600
Density 1.799g/cm3 Boiling Point 669.3ºC at 760 mmHg
Molecular Formula C15H10O7 Melting Point >320 ºC (ethanol )
MSDS N/A Flash Point 258.4ºC

 Use of 6-Hydroxykaempferol


6-Hydroxykaempferol, a flavonoid, is a competitive tyrosinase inhibitor with an IC50 value of 124 μM. 6-Hydroxykaempferol has a Ki value of 148 μM relative to L-DOPA as a substrate and effectively inhibits the activity of the enzyme by binding to the active site of the enzyme[1].

 Names

Name 3,5,6,7-tetrahydroxy-2-(4-hydroxyphenyl)chromen-4-one
Synonym More Synonyms

 6-Hydroxykaempferol Biological Activity

Description 6-Hydroxykaempferol, a flavonoid, is a competitive tyrosinase inhibitor with an IC50 value of 124 μM. 6-Hydroxykaempferol has a Ki value of 148 μM relative to L-DOPA as a substrate and effectively inhibits the activity of the enzyme by binding to the active site of the enzyme[1].
Related Catalog
References

[1]. Hong Gao, et al. Inhibitory effects of 5,6,7-trihydroxyflavones on tyrosinase. Molecules. 2007 Jan 29;12(1):86-97.  

 Chemical & Physical Properties

Density 1.799g/cm3
Boiling Point 669.3ºC at 760 mmHg
Melting Point >320 ºC (ethanol )
Molecular Formula C15H10O7
Molecular Weight 302.23600
Flash Point 258.4ºC
Exact Mass 302.04300
PSA 131.36000
LogP 1.98800
Index of Refraction 1.823
Water Solubility Very slightly soluble (0.24 g/L) (25 ºC)

 Safety Information

Hazard Codes Xi

 Synthetic Route

 Synonyms

3,5,6,7,4'-Pentahydroxy-flaven-4-on
3,4',5,6,7-pentahydroxyflavone
6-Hydroxy-kaempferol
6-Hydroxykaempferol