PfDHODH-IN-2
Modify Date: 2024-01-04 12:29:03
PfDHODH-IN-2 structure
|
Common Name | PfDHODH-IN-2 | ||
|---|---|---|---|---|
| CAS Number | 425629-94-3 | Molecular Weight | 297.757 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 427.5±45.0 °C at 760 mmHg | |
| Molecular Formula | C13H12ClNO3S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 212.3±28.7 °C | |
Use of PfDHODH-IN-2PfDHODH-IN-2, a dihydrothiophenone derivative (Compound 11), is a potent Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH) inhibitor with an IC50 of 1.11 µM. PfDHODH-IN-2 acts as an antimalarial agent and can be used for the research of malaria. |
| Name | PfDHODH-IN-2 |
|---|---|
| Synonym | More Synonyms |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 427.5±45.0 °C at 760 mmHg |
| Molecular Formula | C13H12ClNO3S |
| Molecular Weight | 297.757 |
| Flash Point | 212.3±28.7 °C |
| Exact Mass | 297.022644 |
| LogP | 2.77 |
| Vapour Pressure | 0.0±1.0 mmHg at 25°C |
| Index of Refraction | 1.664 |
| Ethyl 2-[(4-chlorophenyl)amino]-4-oxo-4,5-dihydro-3-thiophenecarboxylate |
| 3-Thiophenecarboxylic acid, 2-[(4-chlorophenyl)amino]-4,5-dihydro-4-oxo-, ethyl ester |