4-Fluoro-2-nitrobenzoic acid

Modify Date: 2025-08-25 19:58:45

4-Fluoro-2-nitrobenzoic acid Structure
4-Fluoro-2-nitrobenzoic acid structure
Common Name 4-Fluoro-2-nitrobenzoic acid
CAS Number 394-01-4 Molecular Weight 185.109
Density 1.6±0.1 g/cm3 Boiling Point 343.8±27.0 °C at 760 mmHg
Molecular Formula C7H4FNO4 Melting Point 147-148°C
MSDS Chinese USA Flash Point 161.7±23.7 °C

 Names

Name 4-Fluoro-2-nitrobenzoic acid
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.6±0.1 g/cm3
Boiling Point 343.8±27.0 °C at 760 mmHg
Melting Point 147-148°C
Molecular Formula C7H4FNO4
Molecular Weight 185.109
Flash Point 161.7±23.7 °C
Exact Mass 185.012436
PSA 83.12000
LogP 1.63
Vapour Pressure 0.0±0.8 mmHg at 25°C
Index of Refraction 1.588
InChIKey YLUCXHMYRQUERW-UHFFFAOYSA-N
SMILES O=C(O)c1ccc(F)cc1[N+](=O)[O-]

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi
Risk Phrases R36/37/38
Safety Phrases S26-S36/37/39
RIDADR NONH for all modes of transport
HS Code 2916399090

 Synthetic Route

~33%

4-Fluoro-2-nitrobenzoic acid Structure

4-Fluoro-2-nitr...

CAS#:394-01-4

Literature: Uchikawa, Osamu; Mitsui, Keita; Asakawa, Akiko; Morimoto, Shigeru; Yamamoto, Masataka; Kimura, Hiroyuki; Moriya, Takeo; Mizuno, Masahiro Patent: US2003/187014 A1, 2003 ;

~82%

4-Fluoro-2-nitrobenzoic acid Structure

4-Fluoro-2-nitr...

CAS#:394-01-4

Literature: F. HOFFMANN-LA ROCHE AG Patent: WO2004/54985 A1, 2004 ; Location in patent: Page 17 ;

~73%

4-Fluoro-2-nitrobenzoic acid Structure

4-Fluoro-2-nitr...

CAS#:394-01-4

Literature: Protiva, Miroslav; Jilek, Jiri; Rajsner, Miroslav; Pomykacek, Josef; Ryska, Miroslav; et al. Collection of Czechoslovak Chemical Communications, 1986 , vol. 51, # 3 p. 698 - 722

~%

4-Fluoro-2-nitrobenzoic acid Structure

4-Fluoro-2-nitr...

CAS#:394-01-4

Literature: Protiva, Miroslav; Jilek, Jiri; Rajsner, Miroslav; Pomykacek, Josef; Ryska, Miroslav; et al. Collection of Czechoslovak Chemical Communications, 1986 , vol. 51, # 3 p. 698 - 722

~%

4-Fluoro-2-nitrobenzoic acid Structure

4-Fluoro-2-nitr...

CAS#:394-01-4

Literature: Adlerova,E. et al. Collection of Czechoslovak Chemical Communications, 1960 , vol. 25, p. 784 - 796

~%

4-Fluoro-2-nitrobenzoic acid Structure

4-Fluoro-2-nitr...

CAS#:394-01-4

Literature: Protiva, Miroslav; Jilek, Jiri; Rajsner, Miroslav; Pomykacek, Josef; Ryska, Miroslav; et al. Collection of Czechoslovak Chemical Communications, 1986 , vol. 51, # 3 p. 698 - 722

~%

4-Fluoro-2-nitrobenzoic acid Structure

4-Fluoro-2-nitr...

CAS#:394-01-4

Literature: Protiva, Miroslav; Jilek, Jiri; Rajsner, Miroslav; Pomykacek, Josef; Ryska, Miroslav; et al. Collection of Czechoslovak Chemical Communications, 1986 , vol. 51, # 3 p. 698 - 722

~%

4-Fluoro-2-nitrobenzoic acid Structure

4-Fluoro-2-nitr...

CAS#:394-01-4

Literature: Adlerova,E. et al. Collection of Czechoslovak Chemical Communications, 1960 , vol. 25, p. 784 - 796

~%

4-Fluoro-2-nitrobenzoic acid Structure

4-Fluoro-2-nitr...

CAS#:394-01-4

Literature: van Hove Bulletin de la Classe des Sciences, Academie Royale de Belgique, 1922 , vol. <5> 8, p. 507,527 Chem. Zentralbl., 1923 , vol. 94, # I p. 313

 Customs

HS Code 2916399090
Summary 2916399090 other aromatic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

 Articles2

More Articles
Intramolecular general acid catalysis of phosphate monoester hydrolysis. The hydrolysis of salicyl phosphate.

J. Chem. Soc., Perkin Trans. II 2 , 149-155, (1972)

Enhancement of insulin binding to rat white adipocytes at 15 degrees C by 5,5'-dithiobis-(2-nitrobenzoic acid). Independence of the reagent's sulfhydryl group reactivity.

J. Biol. Chem. 263(23) , 11175-82, (1988)

Insulin binding to isolated rat white adipocytes at 15 degrees C, a temperature at which cellular degradation of insulin is negligible, has been found to be described by the Two-step Binding Model: R ...

 Synonyms

Benzoic acid, 4-fluoro-2-nitro-
4-Fluor-2-nitro-benzoesaeure
4-Fluoro-2-nitrobenzoic acid
EINECS 206-890-9
MFCD00024300
4-fluoro-2-nitrobenzoicacid
WNR CF FVQ
2-nitro-4-fluorobenzoic acid
benzoic acid,4-fluoro-2-nitro
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