Picroside II

Modify Date: 2025-08-22 22:36:22

Picroside II structure	Common Name	Picroside II
	CAS Number	39012-20-9	Molecular Weight	512.461
	Density	1.7±0.1 g/cm3	Boiling Point	780.8±60.0 °C at 760 mmHg
	Molecular Formula	C₂₃H₂₈O₁₃	Melting Point	N/A
	MSDS	USA	Flash Point	267.9±26.4 °C

Use of Picroside II

Picroside II, an iridoid compound extracted from Picrorhiza, exhibits anti-inflammatory and anti-apoptotic activities. picroside II alleviates the inflammatory response in sepsis and enhances immune function by inhibiting the activation of NLRP3 inflammasome and NF-κB pathways[1]. Picroside II is an antioxidant, exhibits a significant neuroprotective effect through reducing ROS production and protects the blood-brain barrier (BBB) after cerebral ischemia-reperfusion (CI/R) injury[2].

Name	Picroside II
Synonym	More Synonyms

Description	Picroside II, an iridoid compound extracted from Picrorhiza, exhibits anti-inflammatory and anti-apoptotic activities. picroside II alleviates the inflammatory response in sepsis and enhances immune function by inhibiting the activation of NLRP3 inflammasome and NF-κB pathways[1]. Picroside II is an antioxidant, exhibits a significant neuroprotective effect through reducing ROS production and protects the blood-brain barrier (BBB) after cerebral ischemia-reperfusion (CI/R) injury[2].
Related Catalog	Signaling Pathways >> Protein Tyrosine Kinase/RTK >> ROS Research Areas >> Inflammation/Immunology Research Areas >> Neurological Disease
References	[1]. Huang Y, et al. Picroside II protects against sepsis via suppressing inflammation in mice. Am J Transl Res. 2016 Dec 15;8(12):5519-5531. eCollection 2016. [2]. Zhai L, et al. Picroside II protects the blood-brain barrier by inhibiting the oxidative signaling pathway in cerebral ischemia-reperfusion injury. PLoS One. 2017 Apr 7;12(4):e0174414.

Description

Related Catalog

Signaling Pathways >> Protein Tyrosine Kinase/RTK >> ROS

Research Areas >> Inflammation/Immunology

Research Areas >> Neurological Disease

References

[1]. Huang Y, et al. Picroside II protects against sepsis via suppressing inflammation in mice. Am J Transl Res. 2016 Dec 15;8(12):5519-5531. eCollection 2016.

[2]. Zhai L, et al. Picroside II protects the blood-brain barrier by inhibiting the oxidative signaling pathway in cerebral ischemia-reperfusion injury. PLoS One. 2017 Apr 7;12(4):e0174414.

Density	1.7±0.1 g/cm3
Boiling Point	780.8±60.0 °C at 760 mmHg
Molecular Formula	C₂₃H₂₈O₁₃
Molecular Weight	512.461
Flash Point	267.9±26.4 °C
Exact Mass	512.153015
PSA	197.13000
LogP	-2.50
Vapour Pressure	0.0±2.8 mmHg at 25°C
Index of Refraction	1.681
Storage condition	2-8°C
Water Solubility	ethanol: soluble1mg/mL, clear, colorless

Hazard Codes	Xi
Safety Phrases	24/25
RIDADR	NONH for all modes of transport

AMPHICOSIDE

Amphicoside II

PicrosideII

Vanilloyl catalpol

Picroside-2

6'-VANILLOYL CATALPOL

2-(Hexopyranosyloxy)-1a-(hydroxymethyl)-1a,1b,2,5a,6,6a-hexahydrooxireno[4,5]cyclopenta[1,2-c]pyran-6-yl 4-hydroxy-3-methoxybenzoate

PICROSID II

Benzoic acid, 4-hydroxy-3-methoxy-, 2-(hexopyranosyloxy)-1a,1b,2,5a,6,6a-hexahydro-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-6-yl ester

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Picroside II
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Picroside II
Price: ￥198.0/20mg
Purity: 98.0%
Delivery: 1 Day
Contact: Liu jia
Email: 2130147988@qq.com

DC Chemicals Limited
China
Product Name: Picroside Ⅱ
Price: $280.0/20mg
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Picroside II
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

Shanghai Amole Biotechnology Co., Ltd.
China
Product Name: Picroside II
Price: ￥Inquiry/100mg ￥Inquiry/10mg ￥Inquiry/1g ￥Inquiry/250mg
Purity: 95.0%
Delivery: Inquiry
Contact: Xiyao Wang
Email: 3623107365@qq.com

Henan Tianfu Chemical Co., Ltd.
China
Product Name: Picroside II
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Delivery: Inquiry
Contact: Anson
Email: info@tianfuchem.com

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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.