8-Azanebularine
Modify Date: 2025-09-18 08:24:07
8-Azanebularine structure
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Common Name | 8-Azanebularine | ||
|---|---|---|---|---|
| CAS Number | 38874-46-3 | Molecular Weight | 253.21500 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C9H11N5O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of 8-Azanebularine8-Azanebularine, a compound with hydrogen in place of the C6 amino group, inhibits the ADAR2 reaction at high concentrations (IC50=15 mM). 8-Azanebularine is incorporated into an RNA structure recognized by human ADAR2 results in high-affinity binding (KD=2 nM). 8-Azanebularine can be used for the research of ADAR-catalyzed RNA-editing reaction[1]. |
| Name | 8-azanebularine ribonucleoside |
|---|---|
| Synonym | More Synonyms |
| Description | 8-Azanebularine, a compound with hydrogen in place of the C6 amino group, inhibits the ADAR2 reaction at high concentrations (IC50=15 mM). 8-Azanebularine is incorporated into an RNA structure recognized by human ADAR2 results in high-affinity binding (KD=2 nM). 8-Azanebularine can be used for the research of ADAR-catalyzed RNA-editing reaction[1]. |
|---|---|
| Related Catalog | |
| Target |
ADAR2 reaction:15 mM (IC50) ADAR2:2 nM (Kd) |
| References |
| Molecular Formula | C9H11N5O4 |
|---|---|
| Molecular Weight | 253.21500 |
| Exact Mass | 253.08100 |
| PSA | 126.41000 |
| InChIKey | XOUCEKYAMMLQRC-JXOAFFINSA-N |
| SMILES | OCC1OC(n2nnc3cncnc32)C(O)C1O |
| 8-azanebularine |
| 1-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl-β-D-1-deoxy-ribofuranose |
| (2R,3S,4R,5R)-2-Hydroxymethyl-5-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl-tetrahydro-furan-3,4-diol |
| 8-Azanebutarin |