Nicotinamide 1,N6-Ethenoadenine Dinucleotide

Modify Date: 2025-08-25 09:29:44

Nicotinamide 1,N6-Ethenoadenine Dinucleotide Structure
Nicotinamide 1,N6-Ethenoadenine Dinucleotide structure
Common Name Nicotinamide 1,N6-Ethenoadenine Dinucleotide
CAS Number 38806-38-1 Molecular Weight 687.44700
Density N/A Boiling Point N/A
Molecular Formula C23H27N7O14P2 Melting Point N/A
MSDS USA Flash Point N/A
Symbol GHS07
GHS07
Signal Word Warning

 Use of Nicotinamide 1,N6-Ethenoadenine Dinucleotide


Nicotinamide 1,N6-ethenoadenine dinucleotide (ε-NAD) , a fluorescent analogue of NAD, is able to serve as a substrate for the bacterial toxincatalyzed G-ADP ribosylation of signal-transducing G-proteins. Nicotinamide 1,N6-ethenoadenine dinucleotide can be used as a fluorescent substrate for the studies of the ADP ribosylation reaction[1].

 Names

Name Nicotinamide 1,N6-Ethenoadenine Dinucleotide
Synonym More Synonyms

  Biological Activity

Description Nicotinamide 1,N6-ethenoadenine dinucleotide (ε-NAD) , a fluorescent analogue of NAD, is able to serve as a substrate for the bacterial toxincatalyzed G-ADP ribosylation of signal-transducing G-proteins. Nicotinamide 1,N6-ethenoadenine dinucleotide can be used as a fluorescent substrate for the studies of the ADP ribosylation reaction[1].
Related Catalog
References

[1]. Hingorani VN, et al. Fluorescent labeling of signal-transducing G-proteins. Pertussis toxin-catalyzed etheno-ADP ribosylation of transducin. J Biol Chem. 1988 Dec 25;263(36):19804-8.  

 Chemical & Physical Properties

Molecular Formula C23H27N7O14P2
Molecular Weight 687.44700
Exact Mass 687.10900
PSA 319.10000
Storage condition 20°C

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi: Irritant;
Risk Phrases 36/37/38
Safety Phrases 26-36
RIDADR NONH for all modes of transport

 Articles24

More Articles
Hormonal control of ADP-ribosyl cyclase activity in pancreatic acinar cells from rats.

J. Biol. Chem. 278(36) , 33629-36, (2003)

Cyclic ADP-ribose, a metabolite of NAD+ evokes Ca2+ release from intracellular stores in different cells. We have determined the activity of cADPr-producing enzymes (ADP-ribosyl cyclases) in different...

NAD+ analogs substituted in the purine base as substrates for poly(ADP-ribosyl) transferase.

FEBS Lett. 397 , 17-21, (1996)

Poly(ADP-ribosyl) transferase (pADPRT) catalyzes the transfer of the ADP-ribose moiety from NAD+ onto proteins as well as onto protein-bound ADP-ribose. As a result, protein-bound polymers of ADP-ribo...

Assay for ADP-ribosyl cyclase by reverse-phase high-performance liquid chromatography.

Anal. Biochem. 299(2) , 218-26, (2001)

Cyclic ADP-ribose (cADPR), a natural metabolite of beta-NAD(+), is a second messenger for Ca(2+) signaling in T cells. As a tool for purification and identification of ADP-ribosyl cyclase(s) in T cell...

 Synonyms

1,N6-ETHENO NAD
Nicotinamide 1,N6-ethenoadenine dinucleotide
Nicotinamide1,N6-EthenoadenineDinucleotide
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