3-epi-betulinic acid

Modify Date: 2024-01-05 18:35:06

3-epi-betulinic acid structure	Common Name	3-epi-betulinic acid
	CAS Number	38736-77-5	Molecular Weight	456.700
	Density	1.1±0.0 g/cm3	Boiling Point	550.0±0.0 °C at 760 mmHg
	Molecular Formula	C₃₀H₄₈O₃	Melting Point	277℃
	MSDS	N/A	Flash Point	300.5±0.0 °C

Use of 3-epi-betulinic acid

Epibetulinic acid, isolated from the root bark of Maytenus cuzcoina and the leaves of Maytenus chiapensis, exhibits potent inhibitory effects on NO and prostaglandin E2 (PGE2) production in mouse macrophages (RAW 264.7) stimulated with bacterial endotoxin with IC50s of 0.7 and 0.6 μM, respectively. Anti-inflammatory activity[1].

Name	Epibetulinic acid
Synonym	More Synonyms

Description	Epibetulinic acid, isolated from the root bark of Maytenus cuzcoina and the leaves of Maytenus chiapensis, exhibits potent inhibitory effects on NO and prostaglandin E2 (PGE2) production in mouse macrophages (RAW 264.7) stimulated with bacterial endotoxin with IC50s of 0.7 and 0.6 μM, respectively. Anti-inflammatory activity[1].
Related Catalog	Signaling Pathways >> Immunology/Inflammation >> NO Synthase Signaling Pathways >> GPCR/G Protein >> Prostaglandin Receptor Research Areas >> Inflammation/Immunology
Target	PGE2:0.6 μM (IC50) NO:0.7 μM (IC50)
References	[1]. Reyes CP, et al. Activity of lupane triterpenoids from Maytenus species as inhibitors of nitric oxide and prostaglandin E2. Bioorg Med Chem. 2006 Mar 1;14(5):1573-9.

Density	1.1±0.0 g/cm3
Boiling Point	550.0±0.0 °C at 760 mmHg
Melting Point	277℃
Molecular Formula	C₃₀H₄₈O₃
Molecular Weight	456.700
Flash Point	300.5±0.0 °C
Exact Mass	456.360352
PSA	57.53000
LogP	8.94
Vapour Pressure	0.0±0.0 mmHg at 25°C
Index of Refraction	1.533
Storage condition	2-8C