38736-77-5

38736-77-5 structure

Name: 3-epi-betulinic acid
Chemical Name: Epibetulinic acid
CAS Number: 38736-77-5
Molecular Formula: C₃₀H₄₈O₃
Molecular Weight: 456.700
Catalog: Biochemical Plant extracts
Create Date: 2018-04-29 08:00:00
Modify Date: 2024-01-05 18:35:06
Epibetulinic acid, isolated from the root bark of Maytenus cuzcoina and the leaves of Maytenus chiapensis, exhibits potent inhibitory effects on NO and prostaglandin E2 (PGE2) production in mouse macrophages (RAW 264.7) stimulated with bacterial endotoxin with IC50s of 0.7 and 0.6 μM, respectively. Anti-inflammatory activity[1].

Name	Epibetulinic acid
Synonyms	(3β,17α)-3-Hydroxylup-20(29)-en-28-oic acid Betulininsaeure Lup-20(29)-en-28-oic acid, 3-hydroxy-, (3β,17α)- (3α)-3-Hydroxylup-20(29)-en-28-oic acid Lup-20(29)-en-28-oic acid, 3-hydroxy-, (3α)- betulic acid Betulin-saeure 3-epi-betulinic acid

Description	Epibetulinic acid, isolated from the root bark of Maytenus cuzcoina and the leaves of Maytenus chiapensis, exhibits potent inhibitory effects on NO and prostaglandin E2 (PGE2) production in mouse macrophages (RAW 264.7) stimulated with bacterial endotoxin with IC50s of 0.7 and 0.6 μM, respectively. Anti-inflammatory activity[1].
Related Catalog	Signaling Pathways >> Immunology/Inflammation >> NO Synthase Signaling Pathways >> GPCR/G Protein >> Prostaglandin Receptor Research Areas >> Inflammation/Immunology
Target	PGE2:0.6 μM (IC50) NO:0.7 μM (IC50)
References	[1]. Reyes CP, et al. Activity of lupane triterpenoids from Maytenus species as inhibitors of nitric oxide and prostaglandin E2. Bioorg Med Chem. 2006 Mar 1;14(5):1573-9.

Precursor 3
473-98-3 4481-62-3 1617-70-5
DownStream 0