29220-16-4

29220-16-4 structure

Name: Dehydrotrametenolic acid
Chemical Name: dehydrotrametenolic acid
CAS Number: 29220-16-4
Molecular Formula: C₃₀H₄₆O₃
Molecular Weight: 454.684
Catalog: Signaling Pathways Apoptosis Apoptosis
Create Date: 2018-08-25 19:51:22
Modify Date: 2024-01-02 15:22:18
3-Dehydrotrametenolic acid, isolated from the sclerotium of Poria cocos, is a lactate dehydrogenase (LDH) inhibitor. 3-Dehydrotrametenolic acid promotes adipocyte differentiation in vitro and acts as an insulin sensitizer in vivo. 3-Dehydrotrametenolic acid induces apoptosis and has anticancer activity[1][2].

Name	dehydrotrametenolic acid
Synonyms	3β-hydroxylanosta-7,9(11)24-trien-21-oic acid 3-epidehydrotrametenolic 3-epi-dehydrotrametenolic acid 3β-hydroxylanosta-7,9(11),24-trien-21-oic acid 3-epidehydrotrametenolic acid (3β)-3-Hydroxylanosta-7,9(11),24-trien-21-oic acid Lanosta-7,9(11),24-trien-21-oic acid, 3-hydroxy-, (3β)- 3beta-Hydroxylanosta-7,9(11),24-trien-21-oic acid

Description	3-Dehydrotrametenolic acid, isolated from the sclerotium of Poria cocos, is a lactate dehydrogenase (LDH) inhibitor. 3-Dehydrotrametenolic acid promotes adipocyte differentiation in vitro and acts as an insulin sensitizer in vivo. 3-Dehydrotrametenolic acid induces apoptosis and has anticancer activity[1][2].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> Lactate Dehydrogenase
Target	Lactate dehydrogenase [1]
References	[1]. De Nicola GR, et al. Novel gram-scale production of enantiopure R-sulforaphane from Tuscan black kale seeds. Molecules. 2014 May 27;19(6):6975-86. [2]. Abdull Razis AF, et al. The natural chemopreventive phytochemical R-sulforaphane is a far more potent inducer of the carcinogen-detoxifying enzyme systems in rat liver and lung than the S-isomer. Int J Cancer. 2011 Jun 15;128(12):2775-82.