2,2'-Bipyridine

Modify Date: 2025-08-20 00:11:50

2,2'-Bipyridine structure	Common Name	2,2'-Bipyridine
	CAS Number	366-18-7	Molecular Weight	156.184
	Density	1.1±0.1 g/cm3	Boiling Point	272.5±0.0 °C at 760 mmHg
	Molecular Formula	C₁₀H₈N₂	Melting Point	70-73 °C(lit.)
	MSDS	Chinese USA	Flash Point	107.2±12.0 °C
	Symbol	GHS06	Signal Word	Danger

Use of 2,2'-Bipyridine

2,2'-Bipyridine is the unique molecular scaffold of the bioactive natural products represented by caerulomycins (CAEs) and collismycins (COLs). 2,2'-Bipyridine is extensively used as the core structure of many chelating ligands by acting as a bridge in the arrangement of the catalytic center[1].

Name	2,2'-bipyridine
Synonym	More Synonyms

Description	2,2'-Bipyridine is the unique molecular scaffold of the bioactive natural products represented by caerulomycins (CAEs) and collismycins (COLs). 2,2'-Bipyridine is extensively used as the core structure of many chelating ligands by acting as a bridge in the arrangement of the catalytic center[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Others >> Others
References	[1]. Chen D, et al. Discovery of caerulomycin/collismycin-type 2,2'-bipyridine natural products in the genomic era. J Ind Microbiol Biotechnol. 2019;46(3-4):459-468.

Density	1.1±0.1 g/cm3
Boiling Point	272.5±0.0 °C at 760 mmHg
Melting Point	70-73 °C(lit.)
Molecular Formula	C₁₀H₈N₂
Molecular Weight	156.184
Flash Point	107.2±12.0 °C
Exact Mass	156.068741
PSA	25.78000
LogP	1.28
Vapour Pressure	0.0±0.5 mmHg at 25°C
Index of Refraction	1.581
Stability	Stable. Incompatible with strong oxidizing agents, most common metals. May be light sensitive.
Water Solubility	5.5 g/L 22 ºC

2,2'-Bipyridine MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DW1750000

CHEMICAL NAME :: 2,2'-Bipyridine

CAS REGISTRY NUMBER :: 366-18-7

BEILSTEIN REFERENCE NO. :: 0113089

LAST UPDATED :: 199701

DATA ITEMS CITED :: 13

MOLECULAR FORMULA :: C10-H8-N2

MOLECULAR WEIGHT :: 156.20

WISWESSER LINE NOTATION :: T6NJ B- BT6NJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 100 mg/kg

TOXIC EFFECTS :: Behavioral - muscle weakness Kidney, Ureter, Bladder - other changes in urine composition Blood - hemorrhage

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 150 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 131 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 330 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 200 mg/kg

TOXIC EFFECTS :: Kidney, Ureter, Bladder - other changes in urine composition Kidney, Ureter, Bladder - other changes

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 8000 mg/kg/40W-I

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Endocrine - tumors

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

DOSE :: 60 mg/kg

SEX/DURATION :: female 12 day(s) after conception

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - craniofacial (including nose and tongue) Reproductive - Specific Developmental Abnormalities - musculoskeletal system

MUTATION DATA

TYPE OF TEST :: Mutation in mammalian somatic cells

TEST SYSTEM :: Rodent - hamster Lung

DOSE/DURATION :: 14500 ug/L

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 300,223,1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 84441 No. of Facilities: 141 (estimated) No. of Industries: 3 No. of Occupations: 3 No. of Employees: 708 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 84441 No. of Facilities: 461 (estimated) No. of Industries: 6 No. of Occupations: 7 No. of Employees: 3684 (estimated) No. of Female Employees: 886 (estimated)

Symbol	GHS06
Signal Word	Danger
Hazard Statements	H301 + H311
Precautionary Statements	P280-P301 + P310-P312
Personal Protective Equipment	Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
Hazard Codes	T:Toxic
Risk Phrases	R25
Safety Phrases	S36/37-S45-S36/37/39-S26
RIDADR	UN 2811 6.1/PG 3
WGK Germany	3
RTECS	DW1750000
Packaging Group	III
Hazard Class	6.1
HS Code	29333999

Precursor 10
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CAS#:7275-43-6 2,2'-Bipyridyl ... CAS#:110-86-1 Pyridine CAS#:5315-25-3 2-Bromo-6-methy... CAS#:2402-78-0 2,6-Dichloropyridine
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DownStream 10
CAS#:4411-80-7 6,6'-Dimethyl-2... CAS#:33421-43-1 2 2'-dipyridyl-... CAS#:7275-43-6 2,2'-Bipyridyl ... CAS#:4392-85-2 6-Cyano-2,2'-bi...
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CAS#:143924-44-1 2-(PIPERIDIN-2-... CAS#:14163-00-9 4-Nitro-2,2'-bi...

HS Code	2933399090
Summary	2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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bipyridine

2-(2-pyridyl)pyridine

α,α'-dipyridine

EINECS 206-674-4

2,2’-Bipyridyl

dipyridyl

2,2'-Bipyridin

2,2-BIPYRIDINE

2-pyridin-2-ylpyridine

2,2′-bipyridine

2,2′-bipyridyl

[2,2]Bipyridinyl

α,α'-bipyridine

2,2′ bipyridine

2,2’-bipyridine

2,2'-BIPYRIDINE-3,3'-DIOL

2,2'-Bipyridyl

2,2'-Bipyridine

2,2'-Dipyridyl

bipyridyl

bpy

2,2‘-Dipyridyl

2,2`-Bipyridyl

Dipyridyl, 2,2'

MFCD00006212

2,2′-bipyridinyl

2,2'-dipyridine

2,2-Dipyridyl

α,α'-dipyridyl

bipy

α,α'-Bipyridyl

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2,2'-Bipyridine

Use of 2,2'-Bipyridine

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2,2'-Bipyridine Biological Activity

Chemical & Physical Properties

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

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