PGP 4008

Modify Date: 2025-08-25 09:46:18

PGP 4008 Structure
PGP 4008 structure
 Common Name PGP 4008
CAS Number 365565-02-2 Molecular Weight 393.48000
Density N/A Boiling Point N/A
Molecular Formula C26H23N3O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of PGP 4008


PGP-4008 is a specific P-glycoprotein (Pgp) inhibitor. PGP-4008 inhibits tumor growth in a murine syngeneic Pgp-mediated multiple drug resistance (MDR) solid tumor model when given in combination with Doxorubicin[1].

 Names

Name N-(1-Benzyl-2,3-dihydro-1H-pyrrolo[2,3-b]quinolin-4-yl)-2-phenyla cetamide

 PGP 4008 Biological Activity

Description PGP-4008 is a specific P-glycoprotein (Pgp) inhibitor. PGP-4008 inhibits tumor growth in a murine syngeneic Pgp-mediated multiple drug resistance (MDR) solid tumor model when given in combination with Doxorubicin[1].
Related Catalog
References

[1]. Brian D Lee, et al. Synthesis and evaluation of dihydropyrroloquinolines that selectively antagonize P-glycoprotein. J Med Chem. 2004 Mar 11;47(6):1413-22.

 Chemical & Physical Properties

Molecular Formula C26H23N3O
Molecular Weight 393.48000
Exact Mass 393.18400
PSA 48.72000
LogP 5.69320
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Chemsrc provides PGP 4008(CAS#:365565-02-2) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of PGP 4008 are included as well.>> amp version: PGP 4008

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