Ac-Pro-Gly-Pro-OH

Modify Date: 2024-01-24 11:26:01

Ac-Pro-Gly-Pro-OH structure	Common Name	Ac-Pro-Gly-Pro-OH
	CAS Number	292171-04-1	Molecular Weight	311.33
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₄H₂₁N₃O₅	Melting Point	N/A
	MSDS	USA	Flash Point	N/A

Use of Ac-Pro-Gly-Pro-OH

Ac-Pro-Gly-Pro-OH is an endogenous degradation product of extracellular collagen and can be used as CXCR2 agonist. Ac-Pro-Gly-Pro-OH elicits bactericidal activity and inhibits lung inflammation, reducing immune cell apoptosis. Ac-Pro-Gly-Pro-OH enhances the production of type 1 cytokines (IFN-γ and IL-12) but inhibits the production of proinflammatory cytokines. Ac-Pro-Gly-Pro-OH has the potential for the research of sepsis[1][2].

Name	Ac-Pro-Gly-Pro-OH
Synonym	More Synonyms

Description	Ac-Pro-Gly-Pro-OH is an endogenous degradation product of extracellular collagen and can be used as CXCR2 agonist. Ac-Pro-Gly-Pro-OH elicits bactericidal activity and inhibits lung inflammation, reducing immune cell apoptosis. Ac-Pro-Gly-Pro-OH enhances the production of type 1 cytokines (IFN-γ and IL-12) but inhibits the production of proinflammatory cytokines. Ac-Pro-Gly-Pro-OH has the potential for the research of sepsis[1][2].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> CXCR Research Areas >> Inflammation/Immunology Signaling Pathways >> Immunology/Inflammation >> CXCR
Target	CXCR2
References	[1]. Patel DF, et al The multifaceted roles of the matrikine Pro-Gly-Pro in pulmonary health and disease. Eur Respir Rev. 2018 Jun 27;27(148):180017. [2]. Kim SD, et al. Activation of CXCR2 by extracellular matrix degradation product acetylated Pro-Gly-Pro has therapeutic effects against sepsis. Am J Respir Crit Care Med. 2011 Jul 15;184(2):243-51.

Molecular Formula	C₁₄H₂₁N₃O₅
Molecular Weight	311.33
Exact Mass	311.14800
PSA	107.02000

Ac-Pro-Gly-Pro-OH MSDS(Chinese)

ABCB1

N-acetyl-proline-glycine-proline

AcPGP

MDR1 HUMAN MEMBRANE PREPARATION

PGP

Ac-PGP trifluoroacetate salt hydrate

GL Biochem (Shanghai) Ltd.
China
Product Name: Ac-Pro-Gly-Pro-OH
Price: $Inquiry/1kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Jackie Yang

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