G3335

Modify Date: 2025-08-21 19:47:24

G3335 Structure
G3335 structure
Common Name G3335
CAS Number 36099-95-3 Molecular Weight 333.33900
Density N/A Boiling Point N/A
Molecular Formula C16H19N3O5 Melting Point N/A
MSDS USA Flash Point N/A

 Use of G3335


H-​Trp-​Glu-​OH is a selective, reversible and cell-permeable PPARγ with a Kd of ~8 µM. H-​Trp-​Glu-​OH might be developed as a possible lead compound in diabetes research[1].

 Names

Name 2-[[2-amino-3-(1H-indol-3-yl)propanoyl]amino]pentanedioic acid
Synonym More Synonyms

 G3335 Biological Activity

Description H-​Trp-​Glu-​OH is a selective, reversible and cell-permeable PPARγ with a Kd of ~8 µM. H-​Trp-​Glu-​OH might be developed as a possible lead compound in diabetes research[1].
Related Catalog
Target

PPARγ:8 μM (Kd)

References

[1]. Ye F, et al. The dipeptide H-Trp-Glu-OH shows highly antagonistic activity against PPARgamma: bioassay with molecular modeling simulation. Chembiochem. 2006 Jan;7(1):74-82.

 Chemical & Physical Properties

Molecular Formula C16H19N3O5
Molecular Weight 333.33900
Exact Mass 333.13200
PSA 145.51000
LogP 1.56310
Storage condition -20℃

 Safety Information

RIDADR NONH for all modes of transport
HS Code 2933990090

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

PPARgamma Antagonist III,G3335
IN1159
TRP-GLU
tryptophylglutamic acid
L-tryptophyl-L-glutamic acid
H-Trp-Glu-OH
PPARg Antagonist III,G3335
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