36099-95-3

36099-95-3 structure

Name: G3335
Chemical Name: 2-[[2-amino-3-(1H-indol-3-yl)propanoyl]amino]pentanedioic acid
CAS Number: 36099-95-3
Molecular Formula: C₁₆H₁₉N₃O₅
Molecular Weight: 333.33900
Catalog: Signaling Pathways Cell Cycle/DNA Damage PPAR
Create Date: 2019-02-17 14:50:32
Modify Date: 2025-08-21 19:47:24
H-Trp-Glu-OH is a selective, reversible and cell-permeable PPARγ with a Kd of ~8 µM. H-Trp-Glu-OH might be developed as a possible lead compound in diabetes research[1].

Name	2-[[2-amino-3-(1H-indol-3-yl)propanoyl]amino]pentanedioic acid
Synonyms	PPARgamma Antagonist III,G3335 IN1159 TRP-GLU tryptophylglutamic acid L-tryptophyl-L-glutamic acid H-Trp-Glu-OH PPARg Antagonist III,G3335

Description	H-Trp-Glu-OH is a selective, reversible and cell-permeable PPARγ with a Kd of ~8 µM. H-Trp-Glu-OH might be developed as a possible lead compound in diabetes research[1].
Related Catalog	Signaling Pathways >> Cell Cycle/DNA Damage >> PPAR Research Areas >> Metabolic Disease
Target	PPARγ:8 μM (Kd)
References	[1]. Ye F, et al. The dipeptide H-Trp-Glu-OH shows highly antagonistic activity against PPARgamma: bioassay with molecular modeling simulation. Chembiochem. 2006 Jan;7(1):74-82.

RIDADR	NONH for all modes of transport
HS Code	2933990090

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%