MDM2/XIAP-IN-1

Modify Date: 2025-08-24 13:50:35

MDM2/XIAP-IN-1 Structure
MDM2/XIAP-IN-1 structure
 Common Name MDM2/XIAP-IN-1
CAS Number 359595-95-2 Molecular Weight 488.60
Density N/A Boiling Point N/A
Molecular Formula C28H28N2O4S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of MDM2/XIAP-IN-1


MDM2/XIAP-IN-1 (compound 14) is an orally active inhibitor of dual MDM2/XIAP. MDM2/XIAP-IN-1 has anti-cancer activity with an IC50 value of 0.3 μM, which can be used in cance rescrch[1].

 Names

Name MDM2/XIAP-IN-1

 MDM2/XIAP-IN-1 Biological Activity

Description MDM2/XIAP-IN-1 (compound 14) is an orally active inhibitor of dual MDM2/XIAP. MDM2/XIAP-IN-1 has anti-cancer activity with an IC50 value of 0.3 μM, which can be used in cance rescrch[1].
Related Catalog
Target

IC50:0.3 μM (EU-1 cell)[1]

References

[1]. Zhongzhi Wu, et al. Discovery of N-(3,4-Dimethylphenyl)-4-(4-isobutyrylphenyl)-2,3,3a,4,5,9b-hexahydrofuro[3,2-c]quinoline-8-sulfonamide as a Potent Dual MDM2/XIAP Inhibitor. Med. Chem. 2021, 64, 4.

 Chemical & Physical Properties

Molecular Formula C28H28N2O4S
Molecular Weight 488.60
InChIKey HLWMVSWXILODEG-UHFFFAOYSA-N
SMILES COC(=O)c1ccc(C2Nc3ccc(S(=O)(=O)Nc4ccc(C)c(C)c4)cc3C3C=CCC32)cc1
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Chemsrc provides MDM2/XIAP-IN-1(CAS#:359595-95-2) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of MDM2/XIAP-IN-1 are included as well.>> amp version: MDM2/XIAP-IN-1

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