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359595-95-2

359595-95-2 structure

359595-95-2 structure

Name: MDM2/XIAP-IN-1
Chemical Name: MDM2/XIAP-IN-1
CAS Number: 359595-95-2
Molecular Formula: C₂₈H₂₈N₂O₄S
Molecular Weight: 488.60
Catalog: Research Areas Cancer
Create Date: 2023-11-25 23:12:35
Modify Date: 2025-08-24 13:50:35
MDM2/XIAP-IN-1 (compound 14) is an orally active inhibitor of dual MDM2/XIAP. MDM2/XIAP-IN-1 has anti-cancer activity with an IC50 value of 0.3 μM, which can be used in cance rescrch[1].

Name	MDM2/XIAP-IN-1

Description	MDM2/XIAP-IN-1 (compound 14) is an orally active inhibitor of dual MDM2/XIAP. MDM2/XIAP-IN-1 has anti-cancer activity with an IC50 value of 0.3 μM, which can be used in cance rescrch[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
Target	IC50:0.3 μM (EU-1 cell)[1]
References	[1]. Zhongzhi Wu, et al. Discovery of N-(3,4-Dimethylphenyl)-4-(4-isobutyrylphenyl)-2,3,3a,4,5,9b-hexahydrofuro[3,2-c]quinoline-8-sulfonamide as a Potent Dual MDM2/XIAP Inhibitor. Med. Chem. 2021, 64, 4.

Molecular Formula	C₂₈H₂₈N₂O₄S
Molecular Weight	488.60

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