MDM2/XIAP-IN-1

Names

[ CAS No. ]:
359595-95-2

[ Name ]:
MDM2/XIAP-IN-1

Biological Activity

[Description]:

MDM2/XIAP-IN-1 (compound 14) is an orally active inhibitor of dual MDM2/XIAP. MDM2/XIAP-IN-1 has anti-cancer activity with an IC50 value of 0.3 μM, which can be used in cance rescrch[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Others >> Others

[Target]

IC50:0.3 μM (EU-1 cell)[1]


[References]

[1]. Zhongzhi Wu, et al. Discovery of N-(3,4-Dimethylphenyl)-4-(4-isobutyrylphenyl)-2,3,3a,4,5,9b-hexahydrofuro[3,2-c]quinoline-8-sulfonamide as a Potent Dual MDM2/XIAP Inhibitor. Med. Chem. 2021, 64, 4.

Chemical & Physical Properties

[ Molecular Formula ]:
C28H28N2O4S

[ Molecular Weight ]:
488.60

Related Compounds

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