TfR-T12 TFA
Modify Date: 2025-09-20 11:27:17
TfR-T12 TFA structure
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Common Name | TfR-T12 TFA | ||
|---|---|---|---|---|
| CAS Number | 344618-30-0 | Molecular Weight | 1490.73 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C71H99N19O15S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of TfR-T12 TFATfR-T12 is a BBB-penetrated transferrin receptor (TfR) binding peptide, displaying a binding affinity in the nM range[1][2]. |
| Name | TfR-T12 |
|---|
| Description | TfR-T12 is a BBB-penetrated transferrin receptor (TfR) binding peptide, displaying a binding affinity in the nM range[1][2]. |
|---|---|
| Related Catalog | |
| In Vitro | TfR-T12 binds to the TfR and is subsequently internalized into TfR-expressing cells[1]. TfR-T12 is a synthetic peptide obtained by phage display, and is able to bind a different site on TfRs compared with transferrin. TfR-T12 can be chemically conjugated with a pegylated lipid derivative, 3-(N-succinimidyloxyglutaryl)aminopropyl- polyethyleneglycol(2000)- carbamyl distearoyl phosphatidylethanolamine (NHS-PEG2000-DSPE), and used as a functional material to construct the multifunctional lipid vesicles[2]. |
| References |
| Molecular Formula | C71H99N19O15S |
|---|---|
| Molecular Weight | 1490.73 |
| InChIKey | DZRUHTLPVFYMDV-YMGLLDFPSA-N |
| SMILES | CSCCC(NC(=O)C1CCCN1C(=O)C1CCCN1C(=O)C(CCCN=C(N)N)NC(=O)C(Cc1cnc[nH]1)NC(=O)C(N)C(C)O)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NC(CO)C(=O)N1CCCC1C(=O)NC(C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)N1CCCC1C(=O)O)C(C)C |