Xenin-8 TFA

Modify Date: 2025-08-29 18:53:22

Xenin-8 TFA Structure
Xenin-8 TFA structure
Common Name Xenin-8 TFA
CAS Number 117442-28-1 Molecular Weight 1046.27000
Density 1.43±0.1 g/cm3(Predicted) Boiling Point N/A
Molecular Formula C51H79N15O9 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Xenin-8 TFA


Xenin-8, a C-terminal octapeptide, is a biologically active fragment of Xenin. Xenin is a 25-amino acid peptide of the neurotensin/xenopsin family. Xenin-8 stimulates basal insulin secretion and potentiates the insulin response to glucose in a dose-dependent manner (EC50=0.16 nM)[1].

 Names

Name Xenin 8
Synonym More Synonyms

 Xenin-8 TFA Biological Activity

Description Xenin-8, a C-terminal octapeptide, is a biologically active fragment of Xenin. Xenin is a 25-amino acid peptide of the neurotensin/xenopsin family. Xenin-8 stimulates basal insulin secretion and potentiates the insulin response to glucose in a dose-dependent manner (EC50=0.16 nM)[1].
Related Catalog
In Vitro Xenin-8 augments Arginine-induced insulin release (by 40%) and potentiates the glucagon responses to both Arginine (by 60%), Carbachol (by 50%). Xenin-8 counteracts the inhibition of glucagon release induced by increasing the glucose concentration[1].
References

[1]. Ramona A Silvestre, et al. Stimulatory effect of xenin-8 on insulin and glucagon secretion in the perfused rat pancreas. Regul Pept. 2003 Aug 15;115(1):25-9.

 Chemical & Physical Properties

Density 1.43±0.1 g/cm3(Predicted)
Molecular Formula C51H79N15O9
Molecular Weight 1046.27000
Exact Mass 1045.62000
PSA 381.83000
LogP 4.40040

 Synonyms

xenopsin-related peptide i
xp-1
his-pro-lys-arg-pro-trp-ile-leu
xenopsin-related peptide 1
h-his-pro-lys-arg-pro-trp-ile-leu-oh
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