Sophoranol

Modify Date: 2024-01-06 13:04:16

Sophoranol structure	Common Name	Sophoranol
	CAS Number	3411-37-8	Molecular Weight	264.36300
	Density	1.25	Boiling Point	N/A
	Molecular Formula	C₁₅H₂₄N₂O₂	Melting Point	169-170 ºC
	MSDS	N/A	Flash Point	N/A

Use of Sophoranol

Sophoranol is an alkaloid that can be isolated from S. flavescens, with antiviral activity. Sophoranol has anti-HBV (hepatitis B virus) activity. Sophoranol shows potent antiviral activities against respiratory syncytial virus (RSV) with an IC50 of 10.4 μg/mL[1][2].

Name	(+)-sophoranol
Synonym	More Synonyms

Description	Sophoranol is an alkaloid that can be isolated from S. flavescens, with antiviral activity. Sophoranol has anti-HBV (hepatitis B virus) activity. Sophoranol shows potent antiviral activities against respiratory syncytial virus (RSV) with an IC50 of 10.4 μg/mL[1][2].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> HBV Signaling Pathways >> Anti-infection >> RSV
Target	IC50: 10.4 μg/mL (RSV)[2]
In Vitro	Sophoranol has a remarkable inhibitory effect on the secretion of HBsAg and HBeAg n in the 2.2.15 cell line[1].
References	[1]. Guan Ye, et al. LC-MS characterization of efficacy substances in serum of experimental animals treated with Sophora flavescens extracts. Biomed Chromatogr. 2007 Jun;21(6):655-60. [2]. Shuang-Cheng Ma, et al. Antiviral Chinese medicinal herbs against respiratory syncytial virus. J Ethnopharmacol. 2002 Feb;79(2):205-11.

Density	1.25
Melting Point	169-170 ºC
Molecular Formula	C₁₅H₂₄N₂O₂
Molecular Weight	264.36300
Exact Mass	264.18400
PSA	43.78000
LogP	0.86240
Storage condition	2-8°C