5'-UMP disodium salt

Modify Date: 2024-01-02 11:31:52

5'-UMP disodium salt Structure
5'-UMP disodium salt structure
Common Name 5'-UMP disodium salt
CAS Number 3387-36-8 Molecular Weight 368.14
Density 1.865g/cm3 Boiling Point N/A
Molecular Formula C9H11N2Na2O9P Melting Point 208-210 °C
MSDS USA Flash Point N/A

 Use of 5'-UMP disodium salt


Uridine 5'-monophosphate disodium salt is component used for RNA synthesis.

 Names

Name Disodium uridine-5'-monophosphate
Synonym More Synonyms

 5'-UMP disodium salt Biological Activity

Description Uridine 5'-monophosphate disodium salt is component used for RNA synthesis.
Related Catalog
References

[1]. Hozumi Y, et al. Orotate phosphoribosyltransferase localizes to the Golgi complex and its expression levels affect the sensitivity to anti-cancer drug 5-fluorouracil. Biomed Res. 2015;36(6):403-9.

 Chemical & Physical Properties

Density 1.865g/cm3
Melting Point 208-210 °C
Molecular Formula C9H11N2Na2O9P
Molecular Weight 368.14
Exact Mass 367.999756
PSA 186.78000
Index of Refraction -14 ° (C=1, H2O)
Storage condition −20°C
Water Solubility 40 g/100 mL (20 ºC)

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
YU7975000
CHEMICAL NAME :
Uridine, 5'-dihydrogen phosphate, disodium salt
CAS REGISTRY NUMBER :
3387-36-8
LAST UPDATED :
199712
DATA ITEMS CITED :
6
MOLECULAR FORMULA :
C9-H11-N2-O9-P.2Na
MOLECULAR WEIGHT :
368.17

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>12 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
TOIZAG Toho Igakkai Zasshi. Journal of Medical Society of Toho University. (Toho Daigaku Igakkai, 21-16, Omori-nishi, 5-chome, Ota-ku, Tokyo 143, Japan) V.1- 1954- Volume(issue)/page/year: 22,618,1975
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
3111 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - ataxia Lungs, Thorax, or Respiration - cyanosis
REFERENCE :
TOIZAG Toho Igakkai Zasshi. Journal of Medical Society of Toho University. (Toho Daigaku Igakkai, 21-16, Omori-nishi, 5-chome, Ota-ku, Tokyo 143, Japan) V.1- 1954- Volume(issue)/page/year: 22,618,1975
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>6 gm/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Skin and Appendages - dermatitis, irritative (after systemic exposure)
REFERENCE :
TOIZAG Toho Igakkai Zasshi. Journal of Medical Society of Toho University. (Toho Daigaku Igakkai, 21-16, Omori-nishi, 5-chome, Ota-ku, Tokyo 143, Japan) V.1- 1954- Volume(issue)/page/year: 22,618,1975
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>12 gm/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
TOIZAG Toho Igakkai Zasshi. Journal of Medical Society of Toho University. (Toho Daigaku Igakkai, 21-16, Omori-nishi, 5-chome, Ota-ku, Tokyo 143, Japan) V.1- 1954- Volume(issue)/page/year: 22,618,1975
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
3394 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - ataxia Lungs, Thorax, or Respiration - cyanosis
REFERENCE :
TOIZAG Toho Igakkai Zasshi. Journal of Medical Society of Toho University. (Toho Daigaku Igakkai, 21-16, Omori-nishi, 5-chome, Ota-ku, Tokyo 143, Japan) V.1- 1954- Volume(issue)/page/year: 22,618,1975
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
3698 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity)
REFERENCE :
TOIZAG Toho Igakkai Zasshi. Journal of Medical Society of Toho University. (Toho Daigaku Igakkai, 21-16, Omori-nishi, 5-chome, Ota-ku, Tokyo 143, Japan) V.1- 1954- Volume(issue)/page/year: 22,618,1975

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi
Risk Phrases R36/37/38
Safety Phrases S22-S24/25
RIDADR NONH for all modes of transport
WGK Germany 2
RTECS YU7975000

 Synonyms

Disodium Uridine-5-Monophosphate
5'-UMP disodium salt
EINECS 222-211-9
Disodium uridine 5'-phosphate
5'-UMP-NA2
5`-UMP,2Na
5'-UMP 2Na Hydrate
Uridine 5'-Monophosphate Disodium Salt Hydrate
disodiumump
disodium salt of uridine 5'-monophosphate
Disodium 5'-O-phosphonatouridine
MFCD00006525
5'-Uridylic Acid Disodium Salt Hydrate
uridine 5'-monophosphate disodium salt
5′-UMP-Na2
5'-Uridylic acid, sodium salt (1:2)
uridine-5'-monophosphoric acid disodium salt
Uridylic acid disodium salt
uridine-5′-monophosphate disodium
UMP 2NA
5'-Uridylic acid disodium salt
Uridine 5‘-monophosphate,disodium salt,hydrate
Uridine-5'--monophosphate,Disodium salt
UMP,NA2
D-uridine-5'-monophosphate disodium salt
Disodium uridine 5'-monophosphate
UMP DISODIUM
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