9-fluoroprednisolone

Modify Date: 2024-01-12 18:37:21

9-fluoroprednisolone Structure
9-fluoroprednisolone structure
Common Name 9-fluoroprednisolone
CAS Number 338-95-4 Molecular Weight 378.435
Density 1.4±0.1 g/cm3 Boiling Point 566.7±50.0 °C at 760 mmHg
Molecular Formula C21H27FO5 Melting Point 274 - 275ºC
MSDS N/A Flash Point 296.5±30.1 °C

 Use of 9-fluoroprednisolone


Isoflupredone belongs to the class of corticosteroids and exerts its effect by binding to glucocorticoid and mineralocorticoid receptors of animals, such as horses. Isoflupredone can be used in wide range of conditions, such as infection and inflammatory diseases[1].

 Names

Name Isoflupredone
Synonym More Synonyms

 9-fluoroprednisolone Biological Activity

Description Isoflupredone belongs to the class of corticosteroids and exerts its effect by binding to glucocorticoid and mineralocorticoid receptors of animals, such as horses. Isoflupredone can be used in wide range of conditions, such as infection and inflammatory diseases[1].
Related Catalog
In Vivo Isoflupredone shows a significant decrease in serum potassium level in horses. Isoflupredone is a potent drug for the treatment of recurrent airway obstruction affected horses[1].
References

[1]. Picandet V, et al. Comparison of efficacy and tolerability of isoflupredone and dexamethasone in the treatment of horses affected with recurrent airway obstruction ('heaves'). Equine Vet J. 2003;35(4):419-424.

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 566.7±50.0 °C at 760 mmHg
Melting Point 274 - 275ºC
Molecular Formula C21H27FO5
Molecular Weight 378.435
Flash Point 296.5±30.1 °C
Exact Mass 378.184265
PSA 94.83000
LogP 1.38
Vapour Pressure 0.0±3.5 mmHg at 25°C
Index of Refraction 1.600
Storage condition 2~8°C

 Safety Information

Hazard Codes Xi

 Synthetic Route

~79%

9-fluoroprednisolone Structure

9-fluoroprednisolone

CAS#:338-95-4

Literature: McLean; Khalil; Heiman; Lee Journal of Pharmaceutical Sciences, 1994 , vol. 83, # 4 p. 476 - 480

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9-fluoroprednisolone Structure

9-fluoroprednisolone

CAS#:338-95-4

Literature: Helvetica Chimica Acta, , vol. 38, p. 1502,1506

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9-fluoroprednisolone Structure

9-fluoroprednisolone

CAS#:338-95-4

Literature: Journal of the American Chemical Society, , vol. 77, p. 4181

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9-fluoroprednisolone Structure

9-fluoroprednisolone

CAS#:338-95-4

Literature: Journal of the American Chemical Society, , vol. 77, p. 4181

~%

9-fluoroprednisolone Structure

9-fluoroprednisolone

CAS#:338-95-4

Literature: Journal of the American Chemical Society, , vol. 77, p. 4181

~%

9-fluoroprednisolone Structure

9-fluoroprednisolone

CAS#:338-95-4

Literature: Journal of the American Chemical Society, , vol. 77, p. 4181

~%

9-fluoroprednisolone Structure

9-fluoroprednisolone

CAS#:338-95-4

Literature: Journal of the American Chemical Society, , vol. 77, p. 4181

~%

9-fluoroprednisolone Structure

9-fluoroprednisolone

CAS#:338-95-4

Literature: US2837464 , ; Tetrahedron, , vol. 18, p. 581,588

 Synonyms

Pregna-1,4-diene-3,20-dione,9-fluoro-11b,17,21-trihydroxy
9-fluoroprednisolone
1-Dehydro-9a-fluorohydrocortisone
(11b)-9-Fluoro-11,17,21-trihydroxypregna-1,4-diene-3,20-dione
9-Fluoro-11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione
9a-fluoroprednisolone
(11β)-9-Fluoro-11,17,21-trihydroxypregna-1,4-diene-3,20-dione
DELTAFLUDROCORTISONE
Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17,21-trihydroxy-, (11β)-