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338-95-4

338-95-4 structure
338-95-4 structure
  • Name: 9-fluoroprednisolone
  • Chemical Name: Isoflupredone
  • CAS Number: 338-95-4
  • Molecular Formula: C21H27FO5
  • Molecular Weight: 378.435
  • Catalog: Research Areas Others
  • Create Date: 2018-09-29 16:10:33
  • Modify Date: 2024-01-12 18:37:21
  • Isoflupredone belongs to the class of corticosteroids and exerts its effect by binding to glucocorticoid and mineralocorticoid receptors of animals, such as horses. Isoflupredone can be used in wide range of conditions, such as infection and inflammatory diseases[1].

Name Isoflupredone
Synonyms Pregna-1,4-diene-3,20-dione,9-fluoro-11b,17,21-trihydroxy
9-fluoroprednisolone
1-Dehydro-9a-fluorohydrocortisone
(11b)-9-Fluoro-11,17,21-trihydroxypregna-1,4-diene-3,20-dione
9-Fluoro-11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione
9a-fluoroprednisolone
(11β)-9-Fluoro-11,17,21-trihydroxypregna-1,4-diene-3,20-dione
DELTAFLUDROCORTISONE
Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17,21-trihydroxy-, (11β)-
Description Isoflupredone belongs to the class of corticosteroids and exerts its effect by binding to glucocorticoid and mineralocorticoid receptors of animals, such as horses. Isoflupredone can be used in wide range of conditions, such as infection and inflammatory diseases[1].
Related Catalog
In Vivo Isoflupredone shows a significant decrease in serum potassium level in horses. Isoflupredone is a potent drug for the treatment of recurrent airway obstruction affected horses[1].
References

[1]. Picandet V, et al. Comparison of efficacy and tolerability of isoflupredone and dexamethasone in the treatment of horses affected with recurrent airway obstruction ('heaves'). Equine Vet J. 2003;35(4):419-424.

Density 1.4±0.1 g/cm3
Boiling Point 566.7±50.0 °C at 760 mmHg
Melting Point 274 - 275ºC
Molecular Formula C21H27FO5
Molecular Weight 378.435
Flash Point 296.5±30.1 °C
Exact Mass 378.184265
PSA 94.83000
LogP 1.38
Vapour Pressure 0.0±3.5 mmHg at 25°C
Index of Refraction 1.600
Storage condition 2~8°C
Hazard Codes Xi

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338-95-4 structure

338-95-4

Literature: McLean; Khalil; Heiman; Lee Journal of Pharmaceutical Sciences, 1994 , vol. 83, # 4 p. 476 - 480

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338-95-4 structure

338-95-4

Literature: Helvetica Chimica Acta, , vol. 38, p. 1502,1506

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338-95-4 structure

338-95-4

Literature: Journal of the American Chemical Society, , vol. 77, p. 4181

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338-95-4 structure

338-95-4

Literature: Journal of the American Chemical Society, , vol. 77, p. 4181

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338-95-4 structure

338-95-4

Literature: Journal of the American Chemical Society, , vol. 77, p. 4181

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338-95-4 structure

338-95-4

Literature: Journal of the American Chemical Society, , vol. 77, p. 4181

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338-95-4 structure

338-95-4

Literature: Journal of the American Chemical Society, , vol. 77, p. 4181

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338-95-4 structure

338-95-4

Literature: US2837464 , ; Tetrahedron, , vol. 18, p. 581,588