(Z)-Thiothixene

Modify Date: 2025-08-26 13:07:15

(Z)-Thiothixene structure	Common Name	(Z)-Thiothixene
	CAS Number	3313-26-6	Molecular Weight	443.62500
	Density	1.269 g/cm3	Boiling Point	599ºC at 760 mmHg
	Molecular Formula	C₂₃H₂₉N₃O₂S₂	Melting Point	114-118ºC
	MSDS	N/A	Flash Point	316.1ºC
	Symbol	GHS07	Signal Word	Warning

Use of (Z)-Thiothixene

(Z)-Thiothixene is an antagonist of serotonergic receptor extracted from patent US 20150141345 A1.

Name	cis-Thiothixene N,N-Dimethyl-9-[3-(4-methyl-1-piperazinyl)propylidene]thioxanthene-2-sulfonamide
Synonym	More Synonyms

Description	(Z)-Thiothixene is an antagonist of serotonergic receptor extracted from patent US 20150141345 A1.
Related Catalog	Signaling Pathways >> GPCR/G Protein >> 5-HT Receptor Signaling Pathways >> Neuronal Signaling >> 5-HT Receptor Research Areas >> Neurological Disease
Target	serotonergic receptor[1]
In Vitro	(Z)-Thiothixene is capable of promoting cell survival and/or plasticity, and/or inhibiting cell death, especially when a toxic agent is exposed to the cells, including neuronal cells[1]. (Z)-Thiothixene is a Z (cis) isomer of thiothixene, as well as synthetic precursor and degradant[2].
References	[1]. Illana Gozes, et al. Novel compounds and methods for inhibiting cell death. US 20150141345 A1. [2]. Severin G. Comprehensive high-performance liquid chromatographic methodology for the determination of thiothixene in bulk drug, finished product, and dissolution testing samples. J Pharm Sci. 1987 Mar;76(3):231-4.

Density	1.269 g/cm3
Boiling Point	599ºC at 760 mmHg
Melting Point	114-118ºC
Molecular Formula	C₂₃H₂₉N₃O₂S₂
Molecular Weight	443.62500
Flash Point	316.1ºC
Exact Mass	443.17000
PSA	77.54000
LogP	4.42730
Index of Refraction	1.643
InChIKey	GFBKORZTTCHDGY-UWVJOHFNSA-N
SMILES	CN1CCN(CCC=C2c3ccccc3Sc3ccc(S(=O)(=O)N(C)C)cc32)CC1
Storage condition	2-8°C

(Z)-Thiothixene MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: XO1420000

CHEMICAL NAME :: Thioxanthene-2-sulfonamide, N,N-dimethyl-9-(3-(4-methyl-1-piperazinyl)propylidene )-, (Z)-

CAS REGISTRY NUMBER :: 3313-26-6

LAST UPDATED :: 199712

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C23-H29-N3-O2-S2

MOLECULAR WEIGHT :: 443.67

WISWESSER LINE NOTATION :: T C666 BS IYJ FSWN1&1 IU3- AT6N DNTJ D1 -C

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 55 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PSYPAG Psychopharmacologia (Berlin). (Berlin, Ger.) V.1-46, 1959-76. For publisher information, see PSCHDL. Volume(issue)/page/year: 12,142,1968

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 100 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 13,17,1970

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302
Precautionary Statements	P301 + P312 + P330
Hazard Codes	Xn: Harmful;
Risk Phrases	R22
RIDADR	NONH for all modes of transport
RTECS	XO1420000

Thiothixene

MFCD00079574

N,N-Dimethyl-9-[3-(4-methyl-1-piperazinyl)propylidene]thioxanthene-2-sulfonamide

cis-Thiothixene

(Z)-Thiothixene

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: (Z)-Thiothixene
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Purity: 98.0%
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Henan Tianfu Chemical Co., Ltd.
China
Product Name: cis-Thiothixene N,N-Dimethyl-9-[3-(4-methyl-1-piperazinyl)propylidene]thioxanthene-2-sulfonamide
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Delivery: Inquiry
Contact: Anson
Email: info@tianfuchem.com

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Price: $119/10mM*1mLinDMSO

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(Z)-Thiothixene

Use of (Z)-Thiothixene

Names

(Z)-Thiothixene Biological Activity

Chemical & Physical Properties

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

Safety Information

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.