TTP 22

Modify Date: 2025-08-25 16:34:47

TTP 22 Structure
TTP 22 structure
Common Name TTP 22
CAS Number 329907-28-0 Molecular Weight 330.425
Density 1.4±0.1 g/cm3 Boiling Point 575.0±50.0 °C at 760 mmHg
Molecular Formula C16H14N2O2S2 Melting Point N/A
MSDS N/A Flash Point 301.6±30.1 °C

 Use of TTP 22


TTP 22 is a potent CK2 inhibitor, with an IC50 of 100 nM and a Ki of 40 nM.

 Names

Name 3-[5-(4-methylphenyl)thieno[2,3-d]pyrimidin-4-yl]sulfanylpropanoic acid
Synonym More Synonyms

 TTP 22 Biological Activity

Description TTP 22 is a potent CK2 inhibitor, with an IC50 of 100 nM and a Ki of 40 nM.
Related Catalog
Target

CK2:100 nM (IC50)

In Vitro TTP 22 is a potent CK2 inhibitor, with an IC50 of 100 nM and a Ki of 40 nM. TTP 22 shows no effect on other kianses such as Jnk3, Rock1, Tie2, Ask1, Met and FGFR1 at 10 μM[1].
References

[1]. Golub AG, et al. Synthesis and biological evaluation of substituted (thieno[2,3-d]pyrimidin-4-ylthio)carboxylic acids as inhibitors of human protein kinase CK2. Eur J Med Chem. 2011 Mar;46(3):870-6.

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 575.0±50.0 °C at 760 mmHg
Molecular Formula C16H14N2O2S2
Molecular Weight 330.425
Flash Point 301.6±30.1 °C
Exact Mass 330.049683
PSA 116.62000
LogP 4.21
Appearance of Characters white solid
Vapour Pressure 0.0±1.7 mmHg at 25°C
Index of Refraction 1.710
Storage condition -20℃

 Precursor & DownStream

Precursor  2

DownStream  0

 Synonyms

3-{[5-(4-methylphenyl)thieno[2,3-d]pyrimidin-4-yl]thio}propanoic acid
TTP-22
Propanoic acid, 3-[[5-(4-methylphenyl)thieno[2,3-d]pyrimidin-4-yl]thio]-
HMS1423O22
3-{[5-(4-Methylphenyl)thieno[2,3-d]pyrimidin-4-yl]sulfanyl}propanoic acid
TTP22
TTP 22
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