TTP 22
Modify Date: 2025-08-25 16:34:47
TTP 22 structure
|
Common Name | TTP 22 | ||
|---|---|---|---|---|
| CAS Number | 329907-28-0 | Molecular Weight | 330.425 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 575.0±50.0 °C at 760 mmHg | |
| Molecular Formula | C16H14N2O2S2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 301.6±30.1 °C | |
Use of TTP 22TTP 22 is a potent CK2 inhibitor, with an IC50 of 100 nM and a Ki of 40 nM. |
| Name | 3-[5-(4-methylphenyl)thieno[2,3-d]pyrimidin-4-yl]sulfanylpropanoic acid |
|---|---|
| Synonym | More Synonyms |
| Description | TTP 22 is a potent CK2 inhibitor, with an IC50 of 100 nM and a Ki of 40 nM. |
|---|---|
| Related Catalog | |
| Target |
CK2:100 nM (IC50) |
| In Vitro | TTP 22 is a potent CK2 inhibitor, with an IC50 of 100 nM and a Ki of 40 nM. TTP 22 shows no effect on other kianses such as Jnk3, Rock1, Tie2, Ask1, Met and FGFR1 at 10 μM[1]. |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 575.0±50.0 °C at 760 mmHg |
| Molecular Formula | C16H14N2O2S2 |
| Molecular Weight | 330.425 |
| Flash Point | 301.6±30.1 °C |
| Exact Mass | 330.049683 |
| PSA | 116.62000 |
| LogP | 4.21 |
| Appearance of Characters | white solid |
| Vapour Pressure | 0.0±1.7 mmHg at 25°C |
| Index of Refraction | 1.710 |
| InChIKey | RAOULLCLLOGTDA-UHFFFAOYSA-N |
| SMILES | Cc1ccc(-c2csc3ncnc(SCCC(=O)O)c23)cc1 |
| Storage condition | -20℃ |
![5-(4-methylphenyl)thieno[2,3-d]pyrimidin-4(3H)-one structure](https://image.chemsrc.com/caspic/097/17509-21-6.png)
| Precursor 2 | |
|---|---|
| DownStream 0 | |
| 3-{[5-(4-methylphenyl)thieno[2,3-d]pyrimidin-4-yl]thio}propanoic acid |
| TTP-22 |
| Propanoic acid, 3-[[5-(4-methylphenyl)thieno[2,3-d]pyrimidin-4-yl]thio]- |
| HMS1423O22 |
| 3-{[5-(4-Methylphenyl)thieno[2,3-d]pyrimidin-4-yl]sulfanyl}propanoic acid |
| TTP22 |
| TTP 22 |