950225-08-8
950225-08-8 structure
- Name: TTP-8307
- Chemical Name: TTP-8307
- CAS Number: 950225-08-8
- Molecular Formula: C27H21FN4O
- Molecular Weight: 436.49
- Catalog: Signaling Pathways Anti-infection HCV
- Create Date: 2020-01-20 18:27:56
- Modify Date: 2023-01-06 20:04:24
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TTP-8307 is a potent inhibitor of the replication of several Rhinoviruses and Enteroviruses, targets the nonstructural protein 3A, inhibits the replication of coxsackievirus B3 (CVB3 Nancy) with EC50 of 1.2 uM; 3A mutations V45A, I54F, and H57Y confer resistance to TTP-8307.
| Name | TTP-8307 |
|---|
| Description | TTP-8307 is a potent inhibitor of the replication of several Rhinoviruses and Enteroviruses, targets the nonstructural protein 3A, inhibits the replication of coxsackievirus B3 (CVB3 Nancy) with EC50 of 1.2 uM; 3A mutations V45A, I54F, and H57Y confer resistance to TTP-8307. |
|---|---|
| References | References 1. De Palma AM, et al. Antimicrob Agents Chemother. 2009 May;53(5):1850-7. 2. Arita M, et al. J Virol. 2011 Mar;85(5):2364-72. 3. Norder H, et al. Antiviral Res. 2011 Mar;89(3):204-18. View Related Products by Target Enterovirus |
| Molecular Formula | C27H21FN4O |
|---|---|
| Molecular Weight | 436.49 |