Bz-RS-iSer(3-Ph)-OMe

Modify Date: 2024-01-05 11:22:17

Bz-RS-iSer(3-Ph)-OMe Structure
Bz-RS-iSer(3-Ph)-OMe structure
 Common Name Bz-RS-iSer(3-Ph)-OMe
CAS Number 32981-85-4 Molecular Weight 299.321
Density 1.2±0.1 g/cm3 Boiling Point 540.3±50.0 °C at 760 mmHg
Molecular Formula C17H17NO4 Melting Point N/A
MSDS N/A Flash Point 280.6±30.1 °C

 Use of Bz-RS-iSer(3-Ph)-OMe


Bz-RS-iSer(3-Ph)-OMe (compound 2), a Taxol derivative, inhibits HSV replication cycle at low cytotoxicity, blocks mitotic divisions of Vero cells, influences M-MSV induced tumor size and affects immune response by inhibiting PHA-induced T lymphocyte proliferation[1].

 Names

Name methyl (2R,3S)-3-benzamido-2-hydroxy-3-phenylpropanoate
Synonym More Synonyms

 Bz-RS-iSer(3-Ph)-OMe Biological Activity

Description Bz-RS-iSer(3-Ph)-OMe (compound 2), a Taxol derivative, inhibits HSV replication cycle at low cytotoxicity, blocks mitotic divisions of Vero cells, influences M-MSV induced tumor size and affects immune response by inhibiting PHA-induced T lymphocyte proliferation[1].
Related Catalog
References

[1]. Krawczyk E, et al. Cytotoxic, antiviral (in-vitro and in-vivo), immunomodulatory activity and influence on mitotic divisions of three taxol derivatives: 10-deacetyl-baccatin III, methyl (N-benzoyl-(2'R,3'S)-3'-phenylisoserinate) and N-benzoyl-(2'R,3'S)-3'-phenylisoserine. J Pharm Pharmacol. 2005;57(6):791‐797.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 540.3±50.0 °C at 760 mmHg
Molecular Formula C17H17NO4
Molecular Weight 299.321
Flash Point 280.6±30.1 °C
Exact Mass 299.115753
PSA 75.63000
LogP 2.90
Vapour Pressure 0.0±1.5 mmHg at 25°C
Index of Refraction 1.588
Storage condition -20℃

 Safety Information

HS Code 2924299090

 Synthetic Route

 Customs

HS Code 2924299090
Summary 2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Synonyms

Methyl (2R,3S)-3-(benzoylamino)-2-hydroxy-3-phenylpropanoate
Methyl (2R,3S)-N-Benzoyl-3-Phenylisoserine
Benzenepropanoic acid, β-(benzoylamino)-α-hydroxy-, methyl ester, (αR,βS)-
MFCD00673331
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