2-HYDROXY-2-ISOPROPYLSUCCINIC ACID

Modify Date: 2025-08-25 11:00:24

2-HYDROXY-2-ISOPROPYLSUCCINIC ACID Structure
2-HYDROXY-2-ISOPROPYLSUCCINIC ACID structure
Common Name 2-HYDROXY-2-ISOPROPYLSUCCINIC ACID
CAS Number 3237-44-3 Molecular Weight 176.16700
Density 1.342g/cm3 Boiling Point 306.4ºC at 760mmHg
Molecular Formula C7H12O5 Melting Point 144-146ºC(lit.)
MSDS Chinese USA Flash Point 153.3ºC
Symbol GHS07
GHS07
Signal Word Warning

 Use of 2-HYDROXY-2-ISOPROPYLSUCCINIC ACID


α-Isopropylmalate (α-IPM) is the leucine biosynthetic precursor in Yeast[1].

 Names

Name 2-isopropylmalic acid
Synonym More Synonyms

 2-HYDROXY-2-ISOPROPYLSUCCINIC ACID Biological Activity

Description α-Isopropylmalate (α-IPM) is the leucine biosynthetic precursor in Yeast[1].
Related Catalog
In Vitro α-Isopropylmalate (500 μM) increases LEU3 protein (Leu3p)-dependent transcription[1]. α-Isopropylmalate (10 mM, 48 h) increases reporter gene expression in preadipocytes (30A5)[2].

 Chemical & Physical Properties

Density 1.342g/cm3
Boiling Point 306.4ºC at 760mmHg
Melting Point 144-146ºC(lit.)
Molecular Formula C7H12O5
Molecular Weight 176.16700
Flash Point 153.3ºC
Exact Mass 176.06800
PSA 94.83000

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi: Irritant;
Risk Phrases 36/37/38
Safety Phrases 26-37/39
RIDADR NONH for all modes of transport
HS Code 2918199090

 Synthetic Route

~%

2-HYDROXY-2-ISOPROPYLSUCCINIC ACID Structure

2-HYDROXY-2-ISO...

CAS#:3237-44-3

Literature: Tetrahedron Letters, , vol. 21, # 27 p. 2657 - 2660

~%

2-HYDROXY-2-ISOPROPYLSUCCINIC ACID Structure

2-HYDROXY-2-ISO...

CAS#:3237-44-3

Literature: Agricultural and Biological Chemistry, , vol. 55, # 7 p. 1787 - 1792

~%

2-HYDROXY-2-ISOPROPYLSUCCINIC ACID Structure

2-HYDROXY-2-ISO...

CAS#:3237-44-3

Literature: Nishida, Ritsuo; Kim, Chul-Sa; Fukami, Hiroshi; Irie, Ryozo Agricultural and Biological Chemistry, 1991 , vol. 55, # 7 p. 1787 - 1792

~%

2-HYDROXY-2-ISOPROPYLSUCCINIC ACID Structure

2-HYDROXY-2-ISO...

CAS#:3237-44-3

Literature: Agricultural and Biological Chemistry, , vol. 55, # 7 p. 1787 - 1792

~%

2-HYDROXY-2-ISOPROPYLSUCCINIC ACID Structure

2-HYDROXY-2-ISO...

CAS#:3237-44-3

Literature: Agricultural and Biological Chemistry, , vol. 55, # 7 p. 1787 - 1792

~%

2-HYDROXY-2-ISOPROPYLSUCCINIC ACID Structure

2-HYDROXY-2-ISO...

CAS#:3237-44-3

Literature: Journal of Organic Chemistry, , vol. 23, p. 835

~%

2-HYDROXY-2-ISOPROPYLSUCCINIC ACID Structure

2-HYDROXY-2-ISO...

CAS#:3237-44-3

Literature: Journal of Organic Chemistry, , vol. 23, p. 835

~%

2-HYDROXY-2-ISOPROPYLSUCCINIC ACID Structure

2-HYDROXY-2-ISO...

CAS#:3237-44-3

Literature: Tetrahedron Letters, , vol. 21, # 27 p. 2657 - 2660

 Customs

HS Code 2918199090
Summary 2918199090 other carboxylic acids with alcohol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

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 Synonyms

2-hydroxy-2-isopropyl-succinic acid
2-HYDROXY-2-ISOPROPYLSUCCINIC ACID
2-Hydroxy-2-isopropyl-bernsteinsaeure
MFCD00075003
2-Hydroxy-2-isopropylbutanedioic acid
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