Nrf2 activator 16
Modify Date: 2024-01-13 23:19:59
Nrf2 activator 16 structure
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Common Name | Nrf2 activator 16 | ||
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| CAS Number | 321694-20-6 | Molecular Weight | 498.571 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 699.1±65.0 °C at 760 mmHg | |
| Molecular Formula | C24H22N2O6S2 | Melting Point | N/A | |
| MSDS | USA | Flash Point | 376.6±34.3 °C | |
Use of Nrf2 activator 16Nrf2 activator 16 is a potent Keap1-Nrf2 and Keap1-p-p62 protein-protein interaction inhibitor with IC50 of 0.91 uM and 1.8 uM respectively; upregulates Nrf2 response genes measured by a luciferase cell reporter assay. |
| Name | N,N'-1,4-Naphthalenediylbis(4-methoxybenzenesulfonamide) |
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| Synonym | More Synonyms |
| Description | Nrf2 activator 16 is a potent Keap1-Nrf2 and Keap1-p-p62 protein-protein interaction inhibitor with IC50 of 0.91 uM and 1.8 uM respectively; upregulates Nrf2 response genes measured by a luciferase cell reporter assay. |
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| References | References 1. Saito T, et al. Nat Commun. 2016 Jun 27;7:12030. 2. Yasuda D, et al. Bioorg Med Chem Lett. 2016 Dec 15;26(24):5956-5959. 3. Marcotte D, et al. Bioorg Med Chem. 2013 Jul 15;21(14):4011-9. View Related Products by Target Keap1-Nrf2 |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 699.1±65.0 °C at 760 mmHg |
| Molecular Formula | C24H22N2O6S2 |
| Molecular Weight | 498.571 |
| Flash Point | 376.6±34.3 °C |
| Exact Mass | 498.091919 |
| LogP | 4.81 |
| Vapour Pressure | 0.0±2.2 mmHg at 25°C |
| Index of Refraction | 1.675 |
| RIDADR | NONH for all modes of transport |
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| N,N'-Naphthalene-1,4-Diylbis(4-Methoxybenzenesulfonamide) |
| Benzenesulfonamide, N,N'-1,4-naphthalenediylbis[4-methoxy- |
| N,N'-1,4-Naphthalenediylbis(4-methoxybenzenesulfonamide) |
| 4-methoxy-N-(4-{[(4-methoxyphenyl)sulfonyl]amino}-1-naphthyl)benzenesulfonamide |