2728780-74-1
2728780-74-1 structure
- Name: Nrf2 activator-6
- Chemical Name: Nrf2 activator-6
- CAS Number: 2728780-74-1
- Molecular Formula: C31H37ClFN5O5
- Molecular Weight: 614.11
- Catalog: Signaling Pathways NF-κB Keap1-Nrf2
- Create Date: 2023-01-24 21:46:27
- Modify Date: 2024-01-02 16:33:50
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Nrf2 activator-6, a tetrahydroisoquinoline compound, is a Nrf2 activator. Nrf2 activator-6 has an IC50 of 5 nM for inhibiting the Kelch domain-Nrf2 interaction (WO2021214470A1; Example 4)[1].
| Name | Nrf2 activator-6 |
|---|
| Description | Nrf2 activator-6, a tetrahydroisoquinoline compound, is a Nrf2 activator. Nrf2 activator-6 has an IC50 of 5 nM for inhibiting the Kelch domain-Nrf2 interaction (WO2021214470A1; Example 4)[1]. |
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| Related Catalog | |
| In Vitro | Nrf2 activator-6 (Example 4) 增加 NRF2 介导的基因 NADPH：醌受体氧化还原酶 1 (NQO1) 的 mRNA 水平，EC50 为 0.3 nM[1]。 |
| References |
[1]. Cathy Louise LUCAS, et al. Tetrahydroisoquinoline compounds as nrf2 activators. WO2021214470A1. |
| Molecular Formula | C31H37ClFN5O5 |
|---|---|
| Molecular Weight | 614.11 |