Arg-Glu(EDANS)-(Asn670,Leu671)-Amyloid β/A4 Protein Precursor770 (668-675)-Lys(DABCYL)-Arg trifluoroacetate salt

Modify Date: 2024-02-24 19:06:05

Arg-Glu(EDANS)-(Asn670,Leu671)-Amyloid β/A4 Protein Precursor770 (668-675)-Lys(DABCYL)-Arg trifluoroacetate salt Structure
Arg-Glu(EDANS)-(Asn670,Leu671)-Amyloid β/A4 Protein Precursor770 (668-675)-Lys(DABCYL)-Arg trifluoroacetate salt structure
Common Name Arg-Glu(EDANS)-(Asn670,Leu671)-Amyloid β/A4 Protein Precursor770 (668-675)-Lys(DABCYL)-Arg trifluoroacetate salt
CAS Number 310427-94-2 Molecular Weight 2005.22
Density N/A Boiling Point N/A
Molecular Formula C91H129N25O25S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Arg-Glu(EDANS)-(Asn670,Leu671)-Amyloid β/A4 Protein Precursor770 (668-675)-Lys(DABCYL)-Arg trifluoroacetate salt


RE (EDANS) EVNLDAEFK (DABCYL) R is an EDANS and DABCYL double-labeled peptide,serves as a fluorescent substrate for BACE1(Em=360nm,Ex=528nm). RE (EDANS) EVNLDAEFK (DABCYL) R can be used for BACE1 activity measurement and the enzyme activity level is directly proportional to the fluorescence reaction[1].

 Names

Name Arg-Glu: EDANS-: Asn670,Leu671-Amyloid b/A4 Protein Precursor770: 668-675-Lys: DABCYL-Arg
Synonym More Synonyms

  Biological Activity

Description RE (EDANS) EVNLDAEFK (DABCYL) R is an EDANS and DABCYL double-labeled peptide,serves as a fluorescent substrate for BACE1(Em=360nm,Ex=528nm). RE (EDANS) EVNLDAEFK (DABCYL) R can be used for BACE1 activity measurement and the enzyme activity level is directly proportional to the fluorescence reaction[1].
Related Catalog
References

[1]. Ortega A, et.al. Synthesis and evaluation of arylquinones as BACE1 inhibitors, β-amyloid peptide aggregation inhibitors, and destabilizers of preformed β-amyloid fibrils. Bioorg Med Chem Lett. 2011 Apr 15;21(8):2183-7.  

 Chemical & Physical Properties

Molecular Formula C91H129N25O25S
Molecular Weight 2005.22
Exact Mass 2003.93000
PSA 823.15000
LogP 8.81010

 Safety Information

Safety Phrases 22-24/25
WGK Germany 3

 Synonyms

arg-glu(edans)-glu-val-asn-leu-asp-ala-glu-phe-lys(dabcyl)-arg
h-arg-glu(edans)-glu-val-asn-leu-asp-ala-glu-phe-lys(dabcyl)-arg-oh
arg-glu(edans)-[asn670,leu671]-amyloid b/a4 protein precursor 770 fragment 669-674-(dabcyl)lys-arg
arg-glu(edans)-(asn670,leu671)-app770 (668-675)-lys(dabcyl)-arg
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