MY-673

Modify Date: 2024-02-14 16:08:45

MY-673 Structure
MY-673 structure
Common Name MY-673
CAS Number 2944459-96-3 Molecular Weight 322.31
Density N/A Boiling Point N/A
Molecular Formula C18H14N2O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of MY-673


MY-673 is a colchicine binding site inhibitor (CBSI), that inhibits tubulin polymerization. MY-673 inhibits the ERK signaling pathway, which in turn affects SMAD4 protein expression levels in the TGF-β/SMAD pathway. MY-673 inhibited cell proliferation, migration and induced apoptosis in vivo and in vitro[1].

 Names

Name MY-673

 MY-673 Biological Activity

Description MY-673 is a colchicine binding site inhibitor (CBSI), that inhibits tubulin polymerization. MY-673 inhibits the ERK signaling pathway, which in turn affects SMAD4 protein expression levels in the TGF-β/SMAD pathway. MY-673 inhibited cell proliferation, migration and induced apoptosis in vivo and in vitro[1].
Related Catalog
References

[1]. Song J, et al. Discovery of a novel Coumarin-Dihydroquinoxalone derivative MY-673 as a tubulin polymerization inhibitor capable of inhibiting the ERK pathway with potent anti-gastric cancer activities. Bioorg Chem. 2023 Aug;137:106580.  

 Chemical & Physical Properties

Molecular Formula C18H14N2O4
Molecular Weight 322.31
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