T0901317
Modify Date: 2024-01-02 15:01:56
T0901317 structure
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Common Name | T0901317 | ||
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| CAS Number | 293754-55-9 | Molecular Weight | 481.333 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 470.5±55.0 °C at 760 mmHg | |
| Molecular Formula | C17H12F9NO3S | Melting Point | 116-122° C | |
| MSDS | USA | Flash Point | 238.4±31.5 °C | |
Use of T0901317T0901317 is a potent and selective agonist for LXR and FXR, with EC50s of 50 nM and 5 μM, respectively. |
| Name | N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-(2,2,2-trifluoroethyl)benzenesulfonamide |
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| Synonym | More Synonyms |
| Description | T0901317 is a potent and selective agonist for LXR and FXR, with EC50s of 50 nM and 5 μM, respectively. |
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| Related Catalog | |
| References |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 470.5±55.0 °C at 760 mmHg |
| Melting Point | 116-122° C |
| Molecular Formula | C17H12F9NO3S |
| Molecular Weight | 481.333 |
| Flash Point | 238.4±31.5 °C |
| Exact Mass | 481.039429 |
| PSA | 65.99000 |
| LogP | 4.82 |
| Vapour Pressure | 0.0±1.2 mmHg at 25°C |
| Index of Refraction | 1.491 |
| Storage condition | -20°C |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| RIDADR | NONH for all modes of transport |
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Isomer-specific effects of conjugated linoleic acid on HDL functionality associated with reverse cholesterol transport.
J. Nutr. Biochem. 26(2) , 165-72, (2015) High-density lipoproteins (HDLs) are atheroprotective because of their role in reverse cholesterol transport. The intestine is involved in this process because it synthesizes HDL, removes cholesterol ... |
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RNA binding protein HuR regulates the expression of ABCA1.
J. Lipid Res. 55(6) , 1066-1076, (2014) ABCA1 is a major regulator of cellular cholesterol efflux and plasma HDL biogenesis. Even though the transcriptional activation of ABCA1 is well established, the posttranscriptional regulation of ABCA... |
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Effect of compounds affecting ABCA1 expression and CETP activity on the HDL pathway involved in intestinal absorption of lutein and zeaxanthin.
Lipids 49(12) , 1233-43, (2014) The antioxidant xanthophylls lutein and zeaxanthin are absorbed from the diet in a process involving lipoprotein formation. Selective mechanisms exist for their intestinal uptake and tissue-selective ... |
| N-(2,2,2-TRIFLUOROETHYL)-N-{4-[2,2,2-TRIFLUORO-1-HYDROXY-1-(TRIFLUOROMETHYL)ETHYL]PHENYL}BENZENESULFONAMIDE |
| Benzenesulfonamide, N-(2,2,2-trifluoroethyl)-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]- |
| N-[4-(1,1,1,3,3,3-Hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-(2,2,2-trifluoroethyl)benzenesulfonamide |
| MFCD03412028 |
| N-[4-(1,1,1,3,3,3-Hexafluoro-2-hydroxy-2-propanyl)phenyl]-N-(2,2,2-trifluoroethyl)benzenesulfonamide |
| T0901317 |