CSF1R-IN-15

Modify Date: 2025-08-26 08:51:22

CSF1R-IN-15 structure	Common Name	CSF1R-IN-15
	CAS Number	2925744-43-8	Molecular Weight	358.44
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₂H₂₂N₄O	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of CSF1R-IN-15

CSF1R-IN-15 (compound 23) is an inhibitor targeting CSF1R. The colony-stimulating factor-1 receptor (CSF1R) is a tyrosine kinase embedded in the cell membrane of macrophages. The receptor is activated by colony-stimulating factor-1 (CSF-1) and interleukin-34, and signaling via CSF1R is crucial for the differentiation, proliferation, and survival of macrophages[1].

Name	CSF1R-IN-15

Description	CSF1R-IN-15 (compound 23) is an inhibitor targeting CSF1R. The colony-stimulating factor-1 receptor (CSF1R) is a tyrosine kinase embedded in the cell membrane of macrophages. The receptor is activated by colony-stimulating factor-1 (CSF-1) and interleukin-34, and signaling via CSF1R is crucial for the differentiation, proliferation, and survival of macrophages[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Protein Tyrosine Kinase/RTK >> c-Fms
References	[1]. Aarhus TI, et al. Synthesis and Development of Highly Selective Pyrrolo[2,3-d]pyrimidine CSF1R Inhibitors Targeting the Autoinhibited Form. J Med Chem. 2023 May 25;66(10):6959-6980.

Molecular Formula	C₂₂H₂₂N₄O
Molecular Weight	358.44

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CSF1R-IN-15

Use of CSF1R-IN-15

Names

CSF1R-IN-15 Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.