Prednisolone hemisuccinate

Modify Date: 2024-01-03 12:45:27

Prednisolone hemisuccinate structure	Common Name	Prednisolone hemisuccinate
	CAS Number	2920-86-7	Molecular Weight	460.51700
	Density	0,86 g/cm3	Boiling Point	358 °C400 mm Hg(lit.)
	Molecular Formula	C₂₅H₃₂O₈	Melting Point	28-32 °C(lit.)
	MSDS	N/A	Flash Point	265°C/15mm

Use of Prednisolone hemisuccinate

Prednisolone hemisuccinate is a synthetic glucocorticoid, a derivative of cortisol, which is used to treat a variety of inflammatory and auto-immune conditions.

Name	Prednisolone succinate
Synonym	More Synonyms

Description	Prednisolone hemisuccinate is a synthetic glucocorticoid, a derivative of cortisol, which is used to treat a variety of inflammatory and auto-immune conditions.
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology

Density	0,86 g/cm3
Boiling Point	358 °C400 mm Hg(lit.)
Melting Point	28-32 °C(lit.)
Molecular Formula	C₂₅H₃₂O₈
Molecular Weight	460.51700
Flash Point	265°C/15mm
Exact Mass	460.21000
PSA	138.20000
LogP	1.97330
Vapour Pressure	0mmHg at 25°C
Index of Refraction	1.6
Storage condition	2-8℃

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TU4153400

CHEMICAL NAME :: Pregna-1,4-diene-3,20-dione, 11-beta,17,21-trihydroxy-, 21-(hydrogen succinate)

CAS REGISTRY NUMBER :: 2920-86-7

LAST UPDATED :: 199504

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C25-H32-O8

MOLECULAR WEIGHT :: 460.57

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Parenteral

DOSE :: 50 mg/kg

SEX/DURATION :: female 13 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 36,216,1986

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Parenteral

DOSE :: 75 mg/kg

SEX/DURATION :: female 13 day(s) after conception

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - homeostasis

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 36,216,1986 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X9553 No. of Facilities: 403 (estimated) No. of Industries: 1 No. of Occupations: 5 No. of Employees: 4029 (estimated) No. of Female Employees: 2015 (estimated)

Risk Phrases	61-40
Safety Phrases	S53-S22-S36/37/39-S45
RIDADR	NONH for all modes of transport
RTECS	TU4153400

Succinic anhydride

CAS#:108-30-5

prednisolone

CAS#:50-24-8

~90%

Prednisolone he...

CAS#:2920-86-7

Literature: Wang, Chao; Zhao, Ming; Qiu, Xuecai; Peng, Shiqi Bioorganic and Medicinal Chemistry, 2004 , vol. 12, # 16 p. 4403 - 4421

(5-nitrothien-2...

CAS#:570370-45-5

(5-Nitro-2-thie...

CAS#:20898-85-5

Prednisolone he...

CAS#:2920-86-7

Literature: Ferrer, Sandra; Naughton, Declan P.; Threadgill, Michael D. Tetrahedron, 2003 , vol. 59, # 19 p. 3437 - 3444

Precursor 3
CAS#:108-30-5 Succinic anhydride CAS#:50-24-8 prednisolone CAS#:570370-45-5 (5-nitrothien-2...
DownStream 1
CAS#:50-24-8 prednisolone

MFCD00056465

PREDNISOLONE HEMISUCCINATE

PREDNISOLONE 21-HEMISUCCINATE

prednisolone21-succinate

prednisolonbisuccinat

EINECS 220-861-8

prednisolut

prednisolon hemisuccinate

Prednisolone hemisuccinate (usp)

prednisolonebisuccinate

Prednisolone (hemisuccinate)

Prednisolone hemisuccinate

Use of Prednisolone hemisuccinate

Names