H3B-968
Modify Date: 2024-04-03 12:25:50
H3B-968 structure
|
Common Name | H3B-968 | ||
|---|---|---|---|---|
| CAS Number | 2912294-90-5 | Molecular Weight | 548.46 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C22H18F6N4O4S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of H3B-968H3B-968 is a potent inhibitor of Werner syndrome protein (WRN) (IC50=~10 nM)，which acts function as helicase，ATPase，and exonuclease. WRN exhibits synthetic lethal activity in cancer research. However，H3B-968 inhibits WRN helicase activity，competitively with ATP[1]. |
| Name | H3B-968 |
|---|
| Description | H3B-968 is a potent inhibitor of Werner syndrome protein (WRN) (IC50=~10 nM)，which acts function as helicase，ATPase，and exonuclease. WRN exhibits synthetic lethal activity in cancer research. However，H3B-968 inhibits WRN helicase activity，competitively with ATP[1]. |
|---|---|
| Related Catalog | |
| Target |
Werner syndrome protein (WRN)[1] |
| References |
| Molecular Formula | C22H18F6N4O4S |
|---|---|
| Molecular Weight | 548.46 |